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An Efficient One-Pot Synthesis of Pyrazolopyrimidines, Intermediates for Potential Phosphodiesterase Inhibitors

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Monatshefte für Chemie / Chemical Monthly Aims and scope Submit manuscript

Summary.

A simple high-yielding procedure is presented for the synthesis of pyrazolopyrimidinones overcoming limitations found in earlier work and of considerable utility for the production of intermediates for potential phosphodiesterase inhibitors.

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Authors and Affiliations

  1. Chemistry Department, Faculty of Science, Hashemite University, Zarka-Jordan

    Raid J. Abdel-Jalil, Monther Khanfar & Kayed Abu-Safieh

  2. Chemistry Department, Faculty of Sciences and Arts, University of Jordan, Amman-Jordan

    Samer Al-Gharabli & Mustafa El-Abadelah

  3. Abteilung für Physikalische Biochemie des Physiologisch-chemischen Instituts der Universität Tübingen, D-72076, Tübingen, Germany

    Wolfgang Voelter

Authors
  1. Raid J. Abdel-Jalil
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  2. Monther Khanfar
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  3. Kayed Abu-Safieh
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  4. Samer Al-Gharabli
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  5. Mustafa El-Abadelah
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  6. Wolfgang Voelter
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Corresponding authors

Correspondence to Raid J. Abdel-Jalil or Wolfgang Voelter.

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Abdel-Jalil, R., Khanfar, M., Abu-Safieh, K. et al. An Efficient One-Pot Synthesis of Pyrazolopyrimidines, Intermediates for Potential Phosphodiesterase Inhibitors. Monatshefte für Chemie 136, 619–624 (2005). https://doi.org/10.1007/s00706-004-0252-0

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  • DOI: https://doi.org/10.1007/s00706-004-0252-0

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