Summary.
Two new cyclic dimers of cholic acid were obtained in the reaction of 3-O-acetyl methyl cholate with oxalyl chloride. The oxalates bound the cholate subunits “side-to-side” as a result of acylation of 7α and 12α OH groups in the substrate. The selective deprotection of hydroxy groups at C-3 and C-24 proved to be rather difficult and led to various products depending on the reaction conditions.
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Łotowski, Z., Guzmanński, D. New Cyclic Dimers of Cholic Acid. Monatshefte für Chemie 136, 153–158 (2005). https://doi.org/10.1007/s00706-004-0228-0
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DOI: https://doi.org/10.1007/s00706-004-0228-0