Skip to main content

Advertisement

SpringerLink
Log in

HBV infection in HIV-infected subjects in the state of Piauí, Northeast Brazil

  • Brief Report
  • Published:
Archives of Virology Aims and scope Submit manuscript

Abstract

In this study, the prevalence, genotype frequency, and risk factors for HBV infection in 768 HIV-infected subjects living in Piauí were determined. Forty-six (6.0 %) HIV-positive subjects were reactive for HBsAg and positive for HBV-DNA. Genotypes A (71.8 %), F (23.9 %) and D (4.3 %) were identified. Multivariate analysis revealed an association between HIV-HBV coinfection and male gender, older age groups, unprotected sex, reporting more than ten sexual partners throughout life, STD, and tattooing. This study shows the importance of monitoring sites and professionals who perform tattooing and practice safe sex to prevent the spread of HIV and HBV infections.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1

References

  1. Ganem D, Prince AM (2004) Hepatitis B virus infection-natural history and clinical consequences. N Engl J Med 350:1118–1129

    Article  CAS  PubMed  Google Scholar 

  2. Carey WD (2009) The prevalence and natural history of hepatitis B in the 21st century. Clev Clin J Med 76:S2–S5

    Article  Google Scholar 

  3. Franco E, Bagnato B, Marino MG et al (2012) Hepatitis B: epidemiology and prevention in developing countries. World J Hepatol 4:74–80

    Article  PubMed Central  PubMed  Google Scholar 

  4. Alter MJ (2003) Epidemiology of hepatitis B in Europe and worldwide. J Hepatol 39:S64–S69

    Article  PubMed  Google Scholar 

  5. Shepard CW, Simard EP, Finelli L et al (2006) Hepatitis B virus infection: epidemiology and vaccination. Epidemiol Rev 28:112–125

    Article  PubMed  Google Scholar 

  6. De Almeida Pereira RA, Mussi AD, de Azevedo e Silva VC et al (2006) Hepatitis B virus infection in HIV-positive population in Brazil: results of a survey in the state of Mato Grosso and a comparative analysis with other regions of Brazil. BMC Infect Dis 6:34

    Article  PubMed Central  PubMed  Google Scholar 

  7. Pereira LM, Martelli CM, Merchán-Hamann E et al (2009) Population-based multicentric survey of hepatitis B infection and risk factor differences among three regions in Brazil. Am J Trop Med Hyg 81:240–247

    PubMed  Google Scholar 

  8. Sheng WH, Kao JH, Chen PJ et al (2007) Evolution of hepatitis B serological markers in HIV-infected patients receiving highly active antiretroviral therapy. Clin Infect Dis 45:1221–1229

    Article  PubMed  Google Scholar 

  9. Kim HN, Harrington RD, Crane HM et al (2009) Hepatitis B vaccination in HIV-infected adults: current evidence, recommendations and practical considerations. Int J STD AIDS 20:595–600

    Article  CAS  PubMed  Google Scholar 

  10. Thio C (2009) Hepatitis B and human immunodeficiency virus coinfection. Hepatol 49:S138–S145

    Article  Google Scholar 

  11. De Luca A, Bugarini R, Lepri AC et al (2002) Co-infection with hepatitis viruses and outcome of initial antiretroviral regimens in previously naive HIV-infected subjects. Arch Intern Med 162:2125–2132

    Article  PubMed  Google Scholar 

  12. Thio CL (2003) Hepatitis B in the human immunodeficiency virus-infected patient: epidemiology, natural history, and treatment. Semin Liver Dis 23:125–136

    Article  CAS  PubMed  Google Scholar 

  13. Aires RS, Matos MA, Lopes CL et al (2012) Prevalence of hepatitis B virus infection among tuberculosis patients with or without HIV in Goiânia City, Brazil. J Clin Virol 54:327–331

    Article  CAS  PubMed  Google Scholar 

  14. Mendes-Corrêa MC, Barone AA, Cavalheiro N et al (2000) Prevalence of hepatitis B in the sera of patients with HIV infection in São Paulo, Brazil. Rev Inst Med Trop S Paulo 42:81–85

    Article  PubMed  Google Scholar 

  15. Pavan MH, Aoki FH, Monteiro DT et al (2003) Viral hepatitis in patients infected with human immunodeficiency virus. Braz J Infect Dis 7:253–261

    Article  PubMed  Google Scholar 

  16. Souza MG, Passos AD, Machado AA et al (2004) HIV and hepatitis B virus co-infection: prevalence and risk factors. Rev Soc Bras Med Trop 37:391–395

    PubMed  Google Scholar 

  17. Treitinger A, Spada C, Silva EL et al (1999) Prevalence of serologic markers of HBV and HCV infection in HIV-1 seropositive patients in Florianópolis, Brazil. Braz J Infect Dis 3:1–5

    PubMed  Google Scholar 

  18. Oliveira-Filho AB, Oliveira EH, Castro JAA et al (2012) Epidemiological aspects of HCV infection in HIV-infected individuals in Piauí State, Northeast Brazil. Arch Virol 157:2411–2416

    Article  CAS  PubMed  Google Scholar 

  19. Welzel TM, Miley WJ, Parks TL et al (2006) Real-time PCR assay for detection and quantification of hepatitis B virus genotypes A to G. J Clin Microbiol 44:3325–3333

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  20. Mello FC, Souto FJ, Nabuco LC et al (2007) Hepatitis B virus genotypes circulating in Brazil: molecular characterization of genotype F isolates. BMC Microbiol 7:103

    Article  PubMed Central  PubMed  Google Scholar 

  21. Tamura K, Dudley J, Nei M et al (2007) MEGA4: molecular evolutionary genetics analysis (MEGA) software version 4.0. Mol Biol Evol 24:1596–1599

    Article  CAS  PubMed  Google Scholar 

  22. Araújo TME, Sá LC, Santos AS et al (2012) Prevalence of hepatitis B in users of Piauí central laboratory. Rev Enferm UERJ 20:229–234

    Google Scholar 

  23. Devesa M, Pujol FH (2007) Hepatitis B virus genetic diversity in Latin America. Virus Res 127:177–184

    Article  CAS  PubMed  Google Scholar 

  24. Ferreira CT, Silveira TR (2004) Viral Hepatitis: epidemiological and preventive aspects. Rev Bras Epidemiol 7:473–487

    Article  Google Scholar 

  25. Mendes-Corrêa MC, Gomes-Gouvêa MS, Alvarado-Mora MV (2011) Hepatitis delta in HIV/HBV co-infected patients in Brazil: is it important? Int J Infect Dis 15:828–832

    Article  Google Scholar 

  26. Matos SB, Jesus AL, Pedroza KC et al (2013) Prevalence of serological markers and risk factors for bloodborne pathogens in Salvador, Bahia state, Brazil. Epidemiol Infect 15:181–187

    Article  Google Scholar 

  27. de Nishioka SA, Gyorkos TW, Joseph L et al (2002) Tattooing and risk for transfusion-transmitted diseases: The role of the type, number and design of the tattoos, and the conditions in which they were performed. Epidemiol Infect 128:63–71

    PubMed Central  Google Scholar 

  28. Ribeiro NR, Campos GS, Angelo AL et al (2006) Distribution of hepatitis B virus genotypes among patients with chronic infection. Liver Int 26:636–642

    Article  CAS  PubMed  Google Scholar 

  29. Viana S, Paraná R, Moreira RC et al (2005) High prevalence of hepatitis B virus and hepatitis D virus in the western Brazilian Amazon. Am J Trop Med Hyg 73:808–814

    PubMed  Google Scholar 

Download references

Acknowledgments

This research was funded by CNPQ, CAPES and PN-DST/AIDS/Hepatitis.

Author information

Authors and Affiliations

  1. Centro de Ciências da Saúde, Universidade Federal do Piauí, Teresina, PI, Brazil

    Evaldo H. Oliveira & Roseane M. C. Lima Verde

  2. Instituto de Ciências Biológicas, Universidade Federal do Pará, Belém, PA, Brazil

    Evaldo H. Oliveira, José Alexandre R. Lemos & Antonio C. R. Vallinoto

  3. Associação de Ensino Superior do Piauí, Teresina, PI, Brazil

    Roseane M. C. Lima Verde

  4. Faculdade de Ciências Naturais, Universidade Federal do Pará, Campus do Marajó, Breves, PA, Brazil

    Luiz Marcelo L. Pinheiro

  5. Centro de Hematologia e Hemoterapia do Pará, Belém, PA, Brazil

    Luiz Marcelo L. Pinheiro, Marcos G. Benchimol, José Alexandre R. Lemos & Aldemir B. Oliveira-Filho

  6. Secretaria de Saúde do Piauí, Teresina, PI, Brazil

    Ana Luisa E. D. Aragão

  7. Instituto de Estudos Costeiros, Universidade Federal do Pará, Campus de Bragança, Bragança, PA, Brazil

    Aldemir B. Oliveira-Filho

Authors
  1. Evaldo H. Oliveira
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Roseane M. C. Lima Verde
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Luiz Marcelo L. Pinheiro
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Marcos G. Benchimol
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Ana Luisa E. D. Aragão
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. José Alexandre R. Lemos
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. Aldemir B. Oliveira-Filho
    View author publications

    You can also search for this author in PubMed Google Scholar

  8. Antonio C. R. Vallinoto
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Aldemir B. Oliveira-Filho.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Oliveira, E.H., Lima Verde, R.M.C., Pinheiro, L.M.L. et al. HBV infection in HIV-infected subjects in the state of Piauí, Northeast Brazil. Arch Virol 159, 1193–1197 (2014). https://doi.org/10.1007/s00705-013-1921-2

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00705-013-1921-2

Keywords

Search

Navigation