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Epidemiological aspects of HCV infection in HIV-infected individuals in Piauí State, Northeast Brazil

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Abstract

In this study, the prevalence, genotypic frequency, and risk factors for HCV infection in 768 patients infected with HIV were determined. Fifty-two (6.77 %) HIV-positive individuals had anti-HCV antibodies and 26 (3.39 %) had HCV-RNA. Genotyping results indicated that all RT-PCR samples from patients infected with HCV belonged to genotype 1. Multivariate analysis revealed an association of HIV-HCV coinfection with drug use and having received blood transfusions before 1994. The relatively low prevalence of HCV infection in the HIV-positive population in that region may be a consequence of the small number of drug users in the sample, despite a strong association between HCV infection and drug use.

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Authors and Affiliations

  1. Faculdade de Ciências Naturais, Campus do Marajó-Breves, Universidade Federal do Pará, Breves, PA, Brasil

    Aldemir B. Oliveira-Filho

  2. Laboratório de Biologia Molecular, Centro de Hematologia e Hemoterapia do Pará, Belém, PA, Brasil

    Aldemir B. Oliveira-Filho, Jairo A. A. Castro & José Alexandre R. Lemos

  3. Centro de Ciências da Saúde, Universidade Federal do Piauí, Teresina, PI, Brasil

    Evaldo H. Oliveira

  4. Laboratório Central de Saúde Pública do Piauí, Teresina, PI, Brasil

    Letiano V. Silva

  5. Laboratório de Virologia, Instituto de Ciências Biológicas, Universidade Federal do Pará, Belém, PA, Brasil

    Antonio C. R. Vallinoto & José Alexandre R. Lemos

Authors
  1. Aldemir B. Oliveira-Filho
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  2. Evaldo H. Oliveira
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  3. Jairo A. A. Castro
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  4. Letiano V. Silva
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  5. Antonio C. R. Vallinoto
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  6. José Alexandre R. Lemos
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Correspondence to Aldemir B. Oliveira-Filho.

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Oliveira-Filho, A.B., Oliveira, E.H., Castro, J.A.A. et al. Epidemiological aspects of HCV infection in HIV-infected individuals in Piauí State, Northeast Brazil. Arch Virol 157, 2411–2416 (2012). https://doi.org/10.1007/s00705-012-1435-3

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  • DOI: https://doi.org/10.1007/s00705-012-1435-3

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