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Occurrence and investigation of enteric viral infections in pigs with diarrhea in China

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Abstract

Between February 2011 and February 2012, 985 and 324 samples were collected from diarrheal and healthy pigs, respectively, to detect porcine epidemic diarrhea virus (PEDV), porcine kobuvirus (PKoV), porcine bocavirus (PBoV), porcine group A rotavirus (GARV), and transmissible gastroenteritis virus (TGEV). PEDV and PKoV clearly predominated in diarrheal pigs. Compared to healthy pigs, a substantial prevalence of mixed infections was observed in diarrheal pigs (72.3 %) (P < 0.001). All of the coinfections were grouped into 13 patterns. The results of quantitative PCR showed PEDV in diarrheal pigs had a slightly higher mean viral load than that in healthy pigs (7.9 × 106 versus 2.0 ×105 copies/g of stool), while similar mean viral loads were observed for PKoV and PBoV. These findings reveal the severity of coinfections in diarrheal disease and suggest that attention should be paid to synthetic administration and vaccination for its prevention and control.

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Acknowledgments

This study was supported by grants from the National Basic Research Program (973 Program) (No. 2006CB504404) and the National Natural Science Foundation of China (NSFC) (No.31030065).

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Authors and Affiliations

  1. State Key Laboratory of Agricultural Microbiology, Laboratory of Animal Infectious Diseases, College of Animal Science and Veterinary Medicine, Huazhong Agricultural University, Wuhan, 430070, Hubei, China

    Qian Zhang, Ruiming Hu, Xibiao Tang, Chenglong Wu, Qigai He, Huanchun Chen & Bin Wu

  2. Laboratory of Animal Infectious Diseases and Microbiology, College of Animal Science and Technology, Henan University of Science and Technology, Luoyang, 471003, China

    Zhanqin Zhao

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  1. Qian Zhang
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  2. Ruiming Hu
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  3. Xibiao Tang
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Correspondence to Bin Wu.

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Zhang, Q., Hu, R., Tang, X. et al. Occurrence and investigation of enteric viral infections in pigs with diarrhea in China. Arch Virol 158, 1631–1636 (2013). https://doi.org/10.1007/s00705-013-1659-x

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  • DOI: https://doi.org/10.1007/s00705-013-1659-x

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