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Therapeutic options for nocturnal problems in Parkinson’s disease and atypical parkinsonian disorders

  • Neurology and Preclinical Neurological Studies - Review Article
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Abstract

Sleep disturbances in Parkinson’s disease and parkinsonism (such as atypical parkinsonian disorders like multiple system atrophy, progressive supranuclear palsy, dementia with Lewy bodies and corticobasal degeneration) are multifactorial and as such treatment needs to be tailored to the specific patient case and sleep dysfunction. One also has to consider drug-related effects on sleep architecture. This article provides an overview of the therapeutic options for nocturnal problems in Parkinson`s disease and atypical parkinsonian disorders.

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Acknowledgments

This review presents independent research funded by the National Institute for Health Research (NIHR) Mental Health Biomedical Research Centre and Dementia Unit at South London and Maudsley NHS Foundation Trust and King’s College London. The views expressed are those of the authors and not necessarily those of the NHS, the NIHR or the Department of Health.

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Correspondence to Lisa Klingelhoefer.

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Klingelhoefer, L., Sokolov, E. & Chaudhuri, K.R. Therapeutic options for nocturnal problems in Parkinson’s disease and atypical parkinsonian disorders. J Neural Transm 121 (Suppl 1), 25–31 (2014). https://doi.org/10.1007/s00702-014-1202-6

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  • DOI: https://doi.org/10.1007/s00702-014-1202-6

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