Abstract
Backgrounds
Intra-operative ultrasound (ioUS), and the recently introduced contrast-enhanced ultrasound (CEUS) demonstrated to be an extremely valuable tool in oncological cerebral neurosurgery.
Methods
The authors applied ioUS/CEUS techniques to spinal oncological surgery as showed in the illustrative case of a dorsal hemangiopericytoma.
Results and conclusions
ioUS and CEUS provide real-time information that proved useful in identifying both vascular and parenchymatous tumoral patterns, anatomical relations with nervous structure, plan surgical strategy, and identify residuals. It allows to visualize unexposed anatomical and pathological structures within the parenchyma and is a valuable guide during resection.
This is a preview of subscription content, log in via an institution to check access.
References
Bostrom A, Hans FJ, Reinacher PC, Krings T, Burgel U, Gilsbach JM, Reinges MH (2008) Intramedullary hemangioblastomas: timing of surgery, microsurgical technique and follow-up in 23 patients. Eur Spine J 17:882–886
Della Pepa GM, Sabatino G, Sturiale CL, Marchese E, Puca A, Olivi A, Albanese A (2018) Association of real-time intraoperative contrast enhanced ultrasound (CEUS) and color-Doppler ultrasound in the surgical treatment of spinal cord dural arteriovenous fistulae. A technical note. World Neurosurg. https://doi.org/10.1016/j.wneu.2018.01.101
Hao S, Li D, Ma G, Yang J, Wang G (2013) Application of intraoperative indocyanine green videoangiography for resection of spinal cord hemangioblastoma: advantages and limitations. J Clin Neurosci 20:1269–1275
Liu HG, Yang AC, Chen N, Yang J, Qiu XG, Zhang JG (2013) Hemangiopericytomas in the spine: clinical features, classification, treatment, and long-term follow-up in 26 patients. Neurosurgery 72:16–24 discussion 24
Mattei L, Prada F, Legnani FG, Perin A, Olivi A, DiMeco F (2016) Neurosurgical tools to extend tumor resection in hemispheric low-grade gliomas: conventional and contrast enhanced ultrasonography. Child’s Nerv Syst 32:1907–1914
Prada F, Perin A, Martegani A, Aiani L, Solbiati L, Lamperti M, Casali C, Legnani F, Mattei L, Saladino A, Saini M, DiMeco F (2014) Intraoperative contrast-enhanced ultrasound for brain tumor surgery. Neurosurgery 74:542–552 discussion 552
Prada F, Del Bene M, Saini M, Ferroli P, DiMeco F (2015) Intraoperative cerebral angiosonography with ultrasound contrast agents: how I do it. Acta Neurochir 157:1025–1029
Prada F, Bene MD, Fornaro R, Vetrano IG, Martegani A, Aiani L, Sconfienza LM, Mauri G, Solbiati L, Pollo B, DiMeco F (2016) Identification of residual tumor with intraoperative contrast-enhanced ultrasound during glioblastoma resection. Neurosurg Focus 40:E7
Takami T, Naito K, Yamagata T, Ohata K (2015) Surgical management of spinal intramedullary tumors: radical and safe strategy for benign tumors. Neurol Med Chir 55:317–327
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Conflict of interest
The authors declare that they have no conflict of interest.
Ethical approval
All procedures performed in the study involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.
Informed consent
Informed consent was obtained from all individual participants included in the study.
Electronic supplementary material
Rights and permissions
About this article
Cite this article
Della Pepa, G.M., Mattogno, P.P., La Rocca, G. et al. Real-time intraoperative contrast-enhanced ultrasound (CEUS) in vascularized spinal tumors: a technical note. Acta Neurochir 160, 1259–1263 (2018). https://doi.org/10.1007/s00701-018-3541-9
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00701-018-3541-9