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Portable wireless electrochemical sensing of breviscapine using core–shell ZIFs-derived Co nanoparticles embedded in N-doped carbon nanotube polyhedra-modified electrode

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Abstract

A core–shell ZIF-67@ZIF-8-derived Co nanoparticles embedded in N-doped carbon nanotube polyhedra (Co/C-NCNP) hybrid nanostructure was prepared by a pyrolysis method. The synthesized Co/C-NCNP was modified on the screen-printed carbon electrode and used for the portable wireless sensitive determination of breviscapine (BVC) by differential pulse voltammetry. The Co/C-NCNP had a large surface area and excellent catalytic activity with increasing Co sites to combine with BVC for selective determination, which led to the improvement of the sensitivity of the electrochemical sensor. Under optimized conditions, the constructed sensor had linear ranges from 0.15 to 20.0 µmol/L and 20.0 to 100.0 µmol/L with the limit of detection of 0.014 µmol/L (3S0/S). The sensor was successfully applied to BVC tablet sample analysis with satisfactory results. This work provided the potential applications of zeolitic imidazolate framework-derived nanomaterials in the fabrication of electrochemical sensors for the sensitive detection of drug samples.

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Funding

The authors would like to acknowledge the supports from the Specific Research Fund of the Innovation Platform for Academicians of Hainan Province (YSPTZX202126), the National Natural Science Foundation of China (21964007), the Innovation Platform for Academicians of Hainan Province, and the Open Foundation of Key Laboratory of Laser Technology and Optoelectronic Functional Materials of Hainan Province (2022LTOM02).

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Authors and Affiliations

  1. Hainan Engineering Research Center of Tropical Ocean Advanced Optoelectronic Functional Materials, Hainan International Joint Research Center of Marine Advanced Photoelectric Functional Materials, Key Laboratory of Laser Technology and Optoelectronic Functional Materials of Hainan Province, Key Laboratory of Functional Materials and Photoelectrochemistry of Haikou, College of Chemistry and Chemical Engineering, Hainan Normal University, Haikou, 571158, China

    Zejun Zhang, Yijing Ai, Dan Zhang, Lisi Wang & Wei Sun

  2. College of Chemistry and Chemical Engineering, Zhaotong University, Zhaotong, 657000, China

    Zejun Zhang

  3. College of Mechanical Engineering, Chongqing University of Technology, Chongqing, 400054, China

    Fan Shi

  4. College of Health Sciences, Shandong University of Traditional Chinese Medicine, Jinan, 250355, China

    Xiaoqing Li

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  1. Zejun Zhang
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  2. Fan Shi
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  3. Yijing Ai
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Zhang, Z., Shi, F., Ai, Y. et al. Portable wireless electrochemical sensing of breviscapine using core–shell ZIFs-derived Co nanoparticles embedded in N-doped carbon nanotube polyhedra-modified electrode. Microchim Acta 191, 290 (2024). https://doi.org/10.1007/s00604-024-06298-0

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