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High-efficiency fluorescent coordination polymer nanoparticles co-doped with Ce3+/Tb3+ ions for curcumin detection

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Abstract

Curcumin (Cur) possesses diverse biological and pharmacologic effects. It is widely used as a food additive and therapeutic medicine. A study to determine a sensitive detection method for Cur is necessary and meaningful. In this work, double rare earth ions co-doped fluorescent coordination polymer nanoparticles (CPNPs) were developed for the Cur detection. The CPNPs were synthesized by using adenosine monophosphate (AMP) as bridge ligands via coordination self-assembly with Ce3+ and Tb3+. The AMP-Ce/Tb CPNPs exhibited the characteristic green fluorescence of Tb3+ and had high luminescence efficiency. Under the optimal conditions, the fluorescence intensity of AMP-Ce/Tb CPNPs could be significantly quenched by Cur. The fluorescence quenching extent at λex/λem of 300 nm/544 nm showed a good linear relationship with the Cur concentration in the range of 10 to 1000 nM. The detection limit was as low as 8.0 nM (S/N = 3). This method was successfully applied to the determination of Cur in real samples with satisfactory results. The luminescence mechanism of AMP-Ce/Tb CPNPs and the fluorescence quenching mechanism of the CPNPs by Cur were both examined.

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All data generated or analysed during this study are included in this published article and its supplementary information file.

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Acknowledgements

The authors thank Professor Xibao Gao from Shandong University for the helpful discussion and the real sample analysis support.

Funding

This work was supported by Shandong Provincial Natural Science Foundation, China (grant number ZR2022MB131).

Author information

Authors and Affiliations

  1. School of Chemistry and Chemical Engineering, Shandong University, Jinan, 250100, People’s Republic of China

    Yujie Liu, Ran Gao, Xingcen Liu & Xia Wu

  2. Tai’an Center for Disease Control and Prevention, Tai’an, 271000, People’s Republic of China

    Jinhua Zheng

Authors
  1. Yujie Liu
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  4. Jinhua Zheng
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  5. Xia Wu
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Contributions

YuJie Liu: conceptualization, methodology, validation, formal analysis, investigation, data curation, writing — original draft, writing — review and editing, visualization. Ran Gao: validation and formal analysis. Xingcen Liu: formal analysis and writing — review and editing. Jinhua Zheng: validation and formal analysis. Xia Wu: conceptualization, methodology, resources, writing — review and editing, supervision, project administration.

Corresponding author

Correspondence to Xia Wu.

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The study was approved by the Ethical Committee of Shandong University School of Public Health and was performed in accordance with the ethical standards.

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The authors declare no competing interests.

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Liu, Y., Gao, R., Liu, X. et al. High-efficiency fluorescent coordination polymer nanoparticles co-doped with Ce3+/Tb3+ ions for curcumin detection. Microchim Acta 190, 354 (2023). https://doi.org/10.1007/s00604-023-05933-6

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