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Magnetic solid phase extraction sorbents using methyl-parathion and quinalphos dual-template imprinted polymers coupled with GC-MS for class-selective extraction of twelve organophosphorus pesticides

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Abstract

A novel magnetic dual-template molecularly imprinted polymer (DMIP) was prepared with methyl-parathion and quinalphos as templates. For comparison, a series of single-template polymers with only methyl-parathion (MPMIP) or quinalphos (QPMIP) as template as well as a non-imprinted polymer (NIP) in the absence of the template, were synthesized using the same procedure of DMIP. The obtained MIPs were characterized by scanning electron microscopy(SEM), Fourier transform infrared (FT-IR) spectroscopy, vibrating sample magnetometer (VSM), and X-ray diffraction (XRD). The properties including kinetic effect, thermodynamic effect, selectivity, and reusability of MIPs were investigated . Only DMIP possessed high affinity and good recognition for all twelve OPPs including quinalphos, isazophos, chlorpyrifos-methyl, chlorpyrifos, methidathion, triazophos, profenofos, fenthion, fenitrothion, methyl-parathion, parathion, and paraoxon in comparison to MPMIP, QPMIP, or NIP. Moreover, DMIP was used as magnetic solid phase extraction (MSPE) sorbent for the pre-concentration of twelve OPPs in cabbage samples. The developed DMIP-MSPE-GC-MS method showed high sensitivity, low LODs (1.62–13.9 ng/g), fast adsorption equilibrium (10 min), and acceptable spiked recoveries (81.5–113.4%) with relative standard deviations (RSD) in the range 0.05–7.0% (n = 3). The calibration plots were linear in the range 10–800 ng/mL with coefficients of determination (R2) better 0.99 for all twelve compounds. These results suggest that the DMIP is applicable for rapid determination and high throughput analysis of multi-pesticide residues.

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Abbreviations

OPPs:

Organophosphorus pesticides

DMIP:

Dual-template molecularly imprinted polymer

MPMIP:

Methyl-parathion as template molecularly imprinted polymer

QPMIP:

Quinalphos as template molecularly imprinted polymer

NIP:

Non-imprinted polymer

MSPE:

Magnetic solid phase extraction

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Funding

The research was supported by the National Key Research and Development Programs of China (No. 2017YFC1601600), National “Ten thousand Plan” Scientific and Technological Innovation Leading Talent Project (Feng ZHANG) and Shandong Provincial Key Research and Development Program (SPKR&DP).

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Authors and Affiliations

  1. Institute of Food Safety, Chinese Academy of Inspection & Quarantine, Beijing, China

    Lixia Liu, Minli Yang, Muyi He, Tong Liu, Fengming Chen, Yinlong Li & Feng Zhang

  2. School of Pharmacy, China Medical University, Shenyang, China

    Lixia Liu, Xuesong Feng & Yuan Zhang

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  1. Lixia Liu
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  2. Minli Yang
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  3. Muyi He
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  4. Tong Liu
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Correspondence to Feng Zhang.

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Liu, L., Yang, M., He, M. et al. Magnetic solid phase extraction sorbents using methyl-parathion and quinalphos dual-template imprinted polymers coupled with GC-MS for class-selective extraction of twelve organophosphorus pesticides. Microchim Acta 187, 503 (2020). https://doi.org/10.1007/s00604-020-04465-7

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