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Phosphorene nanocomposite with high environmental stability and antifouling capability for simultaneous sensing of clenbuterol and ractopamine

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Abstract

A series of phosphorene (BP) nanocomposites was prepared to realize simultaneous electrochemical determination of clenbuterol (CLB) and ractopamine (RAC). CLB and RAC are the most commonly used β-agonists in animal-derived food. The BP nanohybrid was obtained by co-decoration with both mono(6-mercapto-6-deoxy)-β-cyclodextrin and poly(3,4-ethylenedioxythiophene) nanoparticles. It displays high stability, antifouling capability, a large electrochemical active surface and good electrochemical response. The electrochemical assisted antifouling strategy was selected by further eliminating the fouling of the electrode surface using continuous cyclic voltammetry. The electrode was employed for electrochemical sensing of CLB and RAC at typical peak voltages of 0.8 and 1.0 V (vs. SCE). Responses are linear in the 0.3–90 μM concentration range for CLB, and from 0.3 to 9.4 μM for RAC under optimal conditions. The limit of detection are 0.14 and 0.12 μM, respectively. The sensor was employed for simultaneous determination of CLB and RAC in (spiked) beef, feed and bovine serum samples with acceptable recoveries.

An electrochemically assisted anti-fouling method for simultaneous voltammetric nanosensing of clenbuterol (CLB) and ractopamine (RAC) in edible cattle product samples using high-stable and anti-foul phosphorene (BP) co-decorated with mono(6-mercapto-6-deoxy)-β-cyclodextrin (S-β-CD) and poly(3,4-ethylenedioxythiophene) (PEDOTNPs).

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Acknowledgements

This study was funded by National Beef Cattle Industry Technology & System (CARS-37), National Natural Science Foundation of China (51662014, 51962007, 31660492), Outstanding Young Talent Program of Jiangxi Province (20171BCB23042), Youth project of Natural Science Foundation of JiangxiProvince (20192ACBL21015, 20192BAB204020), Development and Nutrition of Feed for Beef Cattle in Guangchang County (09005392), Jiangxi Provincial Department of Education (GJJ170260).

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Authors and Affiliations

  1. Jiangxi Province Key Laboratory of Animal Nutrition/Engineering Research Center of Feed Development, Jiangxi Agricultural University, Nanchang, 330045, China

    Yu Ge, Mingren Qu, Lanjiao Xu, Junping Xin & Meifa Li

  2. Institute of Functional Materials and Agricultural Applied Chemistry, Jiangxi Agricultural University, Nanchang, 330045, People’s Republic of China

    Yu Ge, Xiaoqiang Wang, Xiaoning Liao, Mingfang Li & Yangping Wen

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  1. Yu Ge
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Correspondence to Lanjiao Xu or Yangping Wen.

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Highlights

1) An electrochemically assisted anti-foul strategy was designed.

2) High-stable and anti-foul BP nanohybrid was prepared.

3) BP nanohybrid co-decorated with PEDOTNPs and S-β-CD was prepared.

4) BP nanohybrid platform for simultaneous voltammetric sensing of CLB and RAC in edible cattle product samples was fabricated.

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Ge, Y., Qu, M., Xu, L. et al. Phosphorene nanocomposite with high environmental stability and antifouling capability for simultaneous sensing of clenbuterol and ractopamine. Microchim Acta 186, 836 (2019). https://doi.org/10.1007/s00604-019-3908-5

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