Abstract
A glassy carbon electrode was modified with a 3D-networked nanostructure composed of MoS2, reduced graphene oxide and gold nanoparticles (3D-MoS2/rGO/Au). The composites were prepared through in-situ growth of gold nanoparticles on 3D-MoS2/rGO nanosheets via a hydrothermal method. The morphology and electrochemical features of the composite were investigated. The 3D-MoS2/rGO/Au sensor exhibits excellent electrocatalytic activity for simultaneous detection of ascorbic acid (AA), dopamine (DA) and uric acid (UA). The oxidation potentials are well separated at around −0.05 V for AA, 0.06 V for DA and 0.2 V for UA, respectively. The detection limits for individual detection and simultaneous detection (S/N = 3) are 0.93 μM and 1.46 μM for AA, 0.11 μM and 0.15 μM for DA, and 0.74 μM and 0.29 μM for UA. The method was applied to the quantitative analysis of AA, DA, and UA in spiked serum samples with satisfying results.
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J J XD (2014) Sensitive electrochemical sensors for simultaneous determination of ascorbic acid, dopamine, and uric acid based on Au@Pd-reduced graphene oxide nanocomposites. Nanoscale 6(19):11303–11309
Chen J, He P, Bai H, He S, Zhang T, Zhang X, Dong F (2017) Poly(β-cyclodextrin)/carbon quantum dots modified glassy carbon electrode: preparation, characterization and simultaneous electrochemical determination of dopamine, uric acid and tryptophan. Sens Actuators B Chem 252:9–16
Khan MMI, Baek GW, Kim K, Kwon HN, Jin SH (2017) Simultaneous detection of dopamine and uric acid on indium tin oxides modified with cost-effective gas cc hase synthesized single walled carbon nanotubes. Electroanal 29(8):1925–1933
Zhang Y, Zhou Q, Zhao W, Chu W, Zheng J (2016) Array of recessed gold nanoelectrodes formed with polymethylmethacrylate for individual detection of ascorbic acid, dopamine and uric acid. Electrochim Acta 212:25–31
Zhao D, Fan D, Wang J, Xu C (2015) Hierarchical nanoporous platinum-copper alloy for simultaneous electrochemical determination of ascorbic acid, dopamine, and uric acid. Microchim Acta 182(7–8):1345–1352
Yan S, Li X, Xiong Y, Wang M, Yang L, Liu X, Li X, Alshahrani LAM, Liu P, Zhang C (2016) Simultaneous determination of ascorbic acid, dopamine and uric acid using a glassy carbon electrode modified with the nickel(II)-bis(1,10-phenanthroline) complex and single-walled carbon nanotubes. Microchim Acta 183(4):1401–1408
Bindumadhavan K, Srivastava SK, Mahanty S (2013) MoS2-MWCNT hybrids as a superior anode in lithium-ion batteries. Chem Commun 49(18):1823–1825
Cheng Z, He B, Zhou L (2014) A general one-step approach for in situ decoration of MoS2 nanosheets with inorganic nanoparticles. J Mater Chem A 3(3):1042–1048
Hinnemann B, Moses PG, Bonde J, Jorgensen KP, Nielsen JH, Horch S, Chorkendorff I, Norskov JK (2005) Biornimetic hydrogen evolution: MoS2 nanoparticles as catalyst for hydrogen evolution. J Am Chem Soc 127(15):5308–5309
Yang X, Liu W, Xiong M, Zhang Y, Liang T, Yang J, Xu M, Ye J, Chen H (2014) Au nanoparticles on ultrathin MoS2 sheets for plasmonic organic solar cells. J Mater Chem A 2(36):14798–14806
Han J, Xia H, Wu Y, Kong SN, Deivasigamani A, Xu R, Hui KM, Kang Y (2016) Single-layer MoS2 nanosheet grafted upconversion nanoparticles for near-infrared fluorescence imaging-guided deep tissue cancer phototherapy. Nanoscale 8(15):7861–7865
Su S, Sun H, Xu F, Yuwen L, Fan C, Wang L (2014) Direct electrochemistry of glucose oxidase and a biosensor for glucose based on a glass carbon electrode modified with MoS2 nanosheets decorated with gold nanoparticles. Microchim Acta 181(13–14):1497–1503
Ma CB, Qi X, Chen B, Bao S, Yin Z, Wu XJ, Luo Z, Wei J, Zhang HL, Zhang H (2014) MoS2 nanoflower-decorated reduced graphene oxide paper for high-performance hydrogen evolution reaction. Nanoscale 6(11):5624–5629
Su S, Han X, Lu Z, Liu W, Zhu D, Chao J, Fan C, Wang L, Song S, Weng L, Wang L (2017) Facile synthesis of a MoS2-Prussian blue Nanocube Nanohybrid-based electrochemical sensing platform for hydrogen peroxide and carcinoembryonic antigen detection. Appl Mater Interfaces 9(14):12773–12781
Park S-K, Yu S-H, Woo S, Quan B, Lee D-C, Kim MK, Sung Y-E, Piao Y (2013) A simple L-cysteine-assisted method for the growth of MoS2 nanosheets on carbon nanotubes for high-performance lithium ion batteries. Dalton Trans 42(7):2399–2405
Tığ GA, Günendi G, Pekyardımcı Ş (2017) A selective sensor based on Au nanoparticles-graphene oxide-poly(2,6-pyridinedicarboxylic acid) composite for simultaneous electrochemical determination of ascorbic acid, dopamine, and uric acid. J Appl Electrochem (17):1–12
Kun C, Weixiang C (2011) In situ synthesis of MoS2/graphene nanosheet composites with extraordinarily high electrochemical performance for lithium ion batteries. Chem Commun 47(14):4252–4254
Lin X, Ni Y, Kokot S (2016) Electrochemical cholesterol sensor based on cholesterol oxidase and MoS2 -AuNPs modified glassy carbon electrode. Sensors Actuators B Chem 233:100–106
Daemi S, Ashkarran AA, Bahari A, Ghasemi S (2017) Gold nanocages decorated biocompatible amine functionalized graphene as an efficient dopamine sensor platform. J Colloid Interface Sci 494:290–299
Xie J, Zhang H, Li S, Wang R, Sun X, Zhou M, Zhou J, Lou XW, Xie Y (2013) Defect-rich MoS2 ultrathin nanosheets with additional active edge sites for enhanced electrocatalytic hydrogen evolution. Adv Mater 25(40):5807–5813
Chen X, Zhang G, Shi L, Pan S, Liu W, Pan H (2016) Au/ZnO hybrid nanocatalysts impregnated in N-doped graphene for simultaneous determination of ascorbic acid, acetaminophen and dopamine. Mater Sci Eng C Mater 65:80–89
Guo Z, Luo X, Li Y, Li D, Zhao Q, Li M, Ma C, Zhao Y (2017) Simultaneous electrochemical determination of ascorbic acid, dopamine and uric acid based on reduced graphene oxide-Ag/PANI modified glassy carbon electrode. Chem Res Chin Univ 33(3):507–512
Zhu Q, Bao J, Huo D, Yang M, Hou C, Guo J, Chen M, Fa H, Luo X, Ma Y (2017) 3D graphene hydrogel – gold nanoparticles nanocomposite modified glassy carbon electrode for the simultaneous determination of ascorbic acid, dopamine and uric acid. Sensors Actuators B Chem 238:1316–1323
Li Y, Lin H, Peng H, Qi R, Luo C (2016) A glassy carbon electrode modified with MoS2 nanosheets and poly(3,4-ethylenedioxythiophene) for simultaneous electrochemical detection of ascorbic acid, dopamine and uric acid. MicrochimActa 183(9):1–7
Sun H, Chao J, Zuo X, Su S, Liu X, Yuwen L, Fan C, Wang L (2014) Gold nanoparticle-decorated MoS2 nanosheets for simultaneous detection of ascorbic acid, dopamine and uric acid. RSC Adv 4(52):27625
Wang C, Du J, Wang H, Zou CE, Jiang F, Yang P, Du Y (2014) A facile electrochemical sensor based on reduced graphene oxide and Au nanoplates modified glassy carbon electrode for simultaneous detection of ascorbic acid, dopamine and uric acid. Sensors Actuators B Chem 204:302–309
Zhang X, Zhang YC, Ma LX (2016) One-pot facile fabrication of graphene-zinc oxide composite and its enhanced sensitivity for simultaneous electrochemical detection of ascorbic acid, dopamine and uric acid. Sensors Actuators B Chem 227(11):488–496
Cai W, Lai J, Lai T, Xie H, Ye J (2016) Controlled functionalization of flexible graphene fibers for the simultaneous determination of ascorbic acid, dopamine and uric acid. Sensors Actuators B Chem 224:225–232
Acknowledgements
This work was supported by the National Natural Science Foundation of China (NO. 81772290), Chongqing science and technology commission (CSTC2018jcyjAX0062), Graduate research and innovation foundation of Chongqing, China (Grant No. CYB18026), University innovation training program for College Students (201810611104), Brew Microorganisms Technology and Application of Key Laboratory Project in Sichuan Province (No. NJ2018-01) and sharing fund of Chongqing university’ s large equipment.
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Zhao, Y., Zhou, J., Jia, Z. et al. In-situ growth of gold nanoparticles on a 3D-network consisting of a MoS2/rGO nanocomposite for simultaneous voltammetric determination of ascorbic acid, dopamine and uric acid. Microchim Acta 186, 92 (2019). https://doi.org/10.1007/s00604-018-3222-7
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DOI: https://doi.org/10.1007/s00604-018-3222-7