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Diagnosis of hepatitis via nanomaterial-based electrochemical, optical or piezoelectrical biosensors: a review on recent advancements

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Abstract

This review (with 145 refs.) summarizes the progress made in the past years in the field of nanomaterial based rapid detection of hepatitis viruses. Following an introduction into the field (with subsection on the significance of hepatitis and on fundamentals of biosensors), conventional methods for detection of hepatitis are discussed, along with their limitationss. The next section covers electrochemical sensors, with subsections on voltammetric, amperometric, potentiometric, impedimetric and conductometric biosensors. A further large section covers optical methods, with subsections on methods based on fluorescence, photometry, surface plasmon resonance, surface-enhanced Raman scattering and chemiluminescence. A concluding section discusses current challenges and gives an outlook on potential future developments.

A schematic illustration of biosensor components applied for detection of hepatitis viruses.

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Authors and Affiliations

  1. Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, 51664, Iran

    Soodabeh Hassanpour, Behzad Baradaran, Amir Baghbanzadeh & Ahad Mokhtarzadeh

  2. Department of Analytical Chemistry, University of Valencia, Dr. Moliner 50, 46100, Burjassot, Valencia, Spain

    Miguel de la Guardia

  3. Research Center of Advanced Technologies in Medicine, Torbat Heydariyeh University of Medical Sciences, Torbat Heydariyeh, 15169-9s5169, Iran

    Jafar Mosafer

  4. Zabol University of Medical Sciences, Zabol, 9861615881, Iran

    Maryam Hejazi

  5. Department of Biotechnology, Higher Education Institute of Rab-Rashid, Tabriz, 5137873715, Iran

    Ahad Mokhtarzadeh

  6. Pharmaceutical Analysis Research Center, Tabriz University of Medical Sciences, Tabriz, 51664, Iran

    Mohammad Hasanzadeh

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  1. Soodabeh Hassanpour
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  2. Behzad Baradaran
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  3. Miguel de la Guardia
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  7. Ahad Mokhtarzadeh
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Hassanpour, S., Baradaran, B., de la Guardia, M. et al. Diagnosis of hepatitis via nanomaterial-based electrochemical, optical or piezoelectrical biosensors: a review on recent advancements. Microchim Acta 185, 568 (2018). https://doi.org/10.1007/s00604-018-3088-8

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