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Simultaneous voltammetric determination of guanine and adenine by using a glassy carbon electrode modified with a composite consisting of carbon quantum dots and overoxidized poly(2-aminopyridine)

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Abstract

A composite consisting of carbon quantum dots (CQDs) and overoxidized poly(2-aminopyridine) (PAPox) was deposited on a glassy carbon electrode (GCE) through electrochemical polymerization and electrochemical oxidation. The modified GCE was used for the simultaneous determination of guanine and adenine. Electrochemical responses to guanine and adenine were investigated by cyclic voltammetry and differential pulse voltammetry. Owing to the synergistic effect of CQDs and PAPox, two oxidation peaks can be observed, with peaks at 0.81 and 1.13 V (vs. SCE) for guanine and adenine, respectively. The current at the respective peaks has a linear dependence on the concentrations of guanine in the range from 1.0 to 65 μM, and of adenine in the range from 2.0 to 70 μM. The respective detection limits are 0.51 and 0.39 μM (at an S/N ratio of 3). The modified GCE is selective, reproducible and stable.

Schematic of the preparation of a glassy carbon electrode modified with carbon quantum dots and overoxidized poly(2-aminopyridine (CQD/PAPox/GCE), and its application for the simultaneous determination of guanine and adenine.

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Acknowledgements

This work was supported by the Longshan Academic Talent Research Supporting Program of SWUST (17LZX406), the National Science & Technology Supported Program (2014BAC13B05) and the Innovation Found of Southwest University of Science and Technology (17ycx007). We are grateful for the help of Analytical and Testing Center of Southwest University of Science and Technology.

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Authors and Affiliations

  1. School of Materials Science and Engineering, Southwest University of Science and Technology, Mianyang, 621010, Sichuan, People’s Republic of China

    Shaoying He, Ping He, Xiaojuan Zhang, Lingpu Jia, Licheng Du & Hong Lei

  2. Mianyang Kingtiger New Energy Technology Co. Ltd., Mianyang, 621000, Sichuan, People’s Republic of China

    Ping He

  3. Center of Analysis and Test, Southwest University of Science and Technology, Mianyang, 621010, Sichuan, People’s Republic of China

    Xingquan Zhang

  4. Key Laboratory of Solid Waste Treatment and Resource Recycle of Ministry of Education, Southwest University of Science and Technology, Mianyang, 621010, Sichuan, People’s Republic of China

    Faqin Dong

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  1. Shaoying He
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Correspondence to Ping He.

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He, S., He, P., Zhang, X. et al. Simultaneous voltammetric determination of guanine and adenine by using a glassy carbon electrode modified with a composite consisting of carbon quantum dots and overoxidized poly(2-aminopyridine). Microchim Acta 185, 107 (2018). https://doi.org/10.1007/s00604-017-2636-y

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