Abstract
A multi-analyte platform based on a portable instrument is presented that enables oxygen and carbon dioxide to be determined in sample gases. The use of four sensing channels (two channels for each analyte to provide redundancy) warrants high system reliability. The sensing scheme in case of oxygen is based on the quenching of the phosphorescence of the platinum octaethylporphyrin complex. In case of carbon dioxide, a secondary inner-filter effect is exploited that is caused by a pH indicator whose color is reversibly changed. The sensing membranes were placed directly on the detectors and on the light sources so to make additional optical element dispensable, reduce system costs, avoid problems related to optical alignment, optimize the efficiency of data acquisition, and enable facile replacement of sensors. The resulting microcontroller-based system is immune against optical and electrical interferences, contains simple digital signal processing circuitry, and has low power consumption. The response of the system to the two gases was modeled, and calibration curves are corrected for effects of temperature. The instrument was characterized in terms of cross-sensitivity and dynamic response. It can determine oxygen and carbon dioxide in terms of volume percentage.
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Wolfbeis OS (2005) Materials for fluorescence-based optical chemical sensors. J Mater Chem 15:2657–2669
Ramamoorthy R, Dutta PK, Akbar SA (2003) Oxygen sensors: materials, methods, designs and applications. J Mat Sci 38:4271–4282
Nagl S, Wolfbeis OS (2007) Optical multiple chemical sensing: status and current challenges. Analyst 132:507–511
Weigl BH, Holobar A, Trettnak W, Klimant I, Kraus H, O’Leary P, Wolfbeis OS (1994) Optical triple sensor for measuring pH, oxygen and carbon dioxide. J Biotechnol 32:127–138
Leiner MJP (1995) Optical sensors for in vitro blood gas analysis. Sens Actuators B B29:169–173
Leiner MJP (1991) Luminescence chemical sensors for biomedical applications: scope and limitations. Anal Chim Acta 255:209–222
Mason RW, Slovacek RE, Sullivan KJ (2002) Optical sensor and method of operation. US 6,488,891
Liebsch G, Klimant I, Frank B, Holst G, Wolfbeis OS (2000) Luminescence lifetime imaging of oxygen, pH, and carbon dioxide distribution using optical sensors. Appl Spec 54:548–559
Yim JB, Hubbard TW, Melkerson LD, Sexton MA, Fieggen BM (1991) Configuration fiber-optic blood gas sensor bundle and method of making. US 5,047,627
Miller WW, Yafuso M, Yan CF, Hui HK, Arick S (1987) Performance of an in-vivo, continuous blood-gas monitor with disposable probe. Clin Chem 33:1538–1542
Gehrich JL, Lubbers DW, Opitz N, Hansmann DR, Miller WW, Tusa JK, Yafuso M (1986) Optical fluorescence and its application to an intravascular blood gas monitoring system. IEEE Trans Biomed Eng 33:117–132
McGaughey O, Nooney R, McEvoy AK, McDonagh C, MacCraith BD (2005) Development of a multi-analyte integrated optical sensor platform for indoor air-quality monitoring. Proc SPIE-Int Soc Opt Eng 5993:59930R-1-59930R/12
Schiza MV, Nelson MP, Myrick ML, Angel SM (2001) Use of a 2D to 1D dimension reduction fiber-optic array for multiwavelength imaging sensors. Appl Spectrosc 55:217–226
Ferguson JA, Healey BG, Bronk KS, Barnard SM, Walt DR (1997) Simultaneous monitoring of pH, CO2 and O2 using an optical imaging fiber. Anal Chim Acta 340:123–131
Wolfbeis OS, Weis LJ, Leiner MJP, Ziegler WE (1988) Fiber-optics fluorosensor for oxygen and carbon dioxide. Anal Chem 60:2028–2030
Borisov SM, Krause C, Arain S, Wolfbeis OS (2006) Composite material for simultaneous and contactless luminescent sensing and imaging of oxygen and carbon dioxide. Adv Mater 18:1511–1516
McEvoy AK, MacCraith BD, McDonagh C, von Bueltzingsloewen C (2010) Optical CO2 and combined O2/CO2 sensors. WO/2004/077035
Schroeder CR, Neurauter G, Klimant I (2007) Luminescent dual sensor for time-resolved imaging of pCO2 and pO2 in aquatic systems. Microchim Acta 158:205–218
Sanchez-Barragan I, Costa-Fernandez JM, Sanz-Medel A, Valledor M, Campo JC (2006) Room-temperature phosphorescence (RTP) for optical sensing. TrAC Trends Anal Chem 25:958–967
Palma AJ, López-González J, Asensio LJ, Fernandez-Ramos MD, Capitan-Vallvey LF (2007) Microcontroller-based portable instrument for stabilised optical oxygen sensor. Sens Actuators B 121:629–638
Trettnak W, Gruber W, Reininger F, Klimant I (1995) Recent progress in optical oxygen sensor instrumentation. Sens Actuators B 29:219–225
Hauser PC (1995) A solid-state instrument for fluorescence chemical sensors using a blue light-emitting diode of high intensity. Meas Sci Technol 6:1081–1085
Choi MF, Hawkins P (1995) A novel oxygen and/or carbon dioxide-sensitive optical transducer. Talanta 42:483–492
Carvajal MA, Perez de Vargas Sansalvador IM, Palma AJ, Fernandez-Ramos MD, Capitan-Vallvey LF (2010) Hand-held optical instrument for CO2 in gas phase based on sensing film coating optoelectronic elements. Sens Actuators B B144:232–238
Bansal AK, Holzer W, Penzkofer A, Tsuboi T (2006) Absorption and emission spectroscopic characterization of platinum-octaethyl-porphyrin (PtOEP). Chem Phys 330:118–129
Palma AJ, Lopez-Gonzalez J, Asensio LJ, Fernandez-Ramos MD, Capitan-Vallvey LF (2007) Open air calibration with temperature compensation of a luminescence quenching-based oxygen sensor for portable instrumentation. Anal Chem 79:3173–3179
Perez de Vargas-Sansalvador IM, Carvajal MA, Roldan-Munoz OM, Banqueri J, Fernandez-Ramos MD, Capitan-Vallvey LF (2009) Phosphorescent sensing of carbon dioxide based on secondary inner-filter quenching. Anal Chim Acta 655:66–74
Amao Y, Komori T, Nishide H (2005) Rapid responsible optical CO2 sensor of the combination of colorimetric change of a-naphtholphthalein in poly(trimethylsiliylpropyne) layer and internal reference fluorescent porphyrin in polystyrene layer. React Funct Polym 63:35–41
Capitan-Vallvey LF, Asensio LJ, Lopez-Gonzalez J, Fernandez-Ramos MD, Palma AJ (2007) Oxygen-sensing film coated photodetectors for portable instrumentation. Anal Chim Acta 583:166–173
Acknowledgements
We acknowledge financial support from the Ministerio de Ciencia e Innovación (Spain) (Projects CTQ2009-14428-C02-01 and CTQ2009-14428-C02-02) and the Junta de Andalucia (Project P08-FQM-3535). These projects have been partially supported by European Regional Development Funds (ERDF).
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Pérez de Vargas-Sansalvador, I.M., Martinez-Olmos, A., Palma, A.J. et al. Compact optical instrument for simultaneous determination of oxygen and carbon dioxide. Microchim Acta 172, 455–464 (2011). https://doi.org/10.1007/s00604-010-0520-0
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DOI: https://doi.org/10.1007/s00604-010-0520-0