Abstract
A novel method, based on the coupling of ionic liquid-based headspace single-drop microextraction (SDME) with gas chromatography (GC), is developed for the determination of chlorobenzene derivatives. For the SDME of five chlorobenzene derivatives, a 1.0 μL 1-octyl-3-methylimidazolium hexafluorophosphate microdrop is exposed for 20 min to the headspace of a 15 ml aqueous sample containing 20% (w/v) NaCl placed in 25 ml vial at 40 °C. Then, the extractant is directly injected into the injector block of the GC instrument. To avoid ionic liquid leaking into the chromatographic column, a small glass tube is placed in the injection block. Under optimized operation conditions, linear relation between peak areas and analyte concentrations up to 1.5 mg L−1 has been obtained The detection limits range from 0.1 to 0.5 μg L−1 for the various analytes. The relative standard deviations at 1.0 μg L−1 range from 7.7 to 12.4%, and the enrichment factors from 41 to 127. The method is simple and sensitive, and does not suffer from the influence of a solvent peak. Its applicability is demonstrated by the determination of chlorobenzenes in wastewater samples.
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The authors appreciate the support of the National Nature Science Foundation of China (No. 20173040).
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Zhao, F., Lu, S., Du, W. et al. Ionic liquid-based headspace single-drop microextraction coupled to gas chromatography for the determination of chlorobenzene derivatives. Microchim Acta 165, 29–33 (2009). https://doi.org/10.1007/s00604-008-0092-4
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DOI: https://doi.org/10.1007/s00604-008-0092-4