Abstract
We investigated a new laser technique of crushing bilirubin calculi, our aim being to crush calculi in isolation using a minimally invasive procedure. Infrared absorption spectrum analysis of the bilirubin calculi was conducted, revealing maximum absorption spectrum at a wavelength of the C=O stretching vibration of ester binding that exists within the molecular structure of bilirubin calcium. As an experiment to crush calculi using the free-electron laser, we set the laser at the effective irradiation wavelength of ester binding, and conducted noncontact irradiation of the bilirubin calculi. The calculi began to slowly ablate until the irradiated site had been completely obliterated after 20 s of irradiation. Moreover, absorption spectrum analysis of the irradiated site, from a comparison of absorption peak ratios, revealed that absorption peak intensities decreased over time at the absorption wavelength of ester binding. These findings suggest that irradiation of molecular oscillating region wavelengths peculiar to calculi based on infrared absorption spectrum analysis results in the gradual crushing of calculi in isolation by breaking down their molecular structure.
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Received: December 7, 1999 / Accepted: November 20, 2000
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Watanabe, M., Kajiwara, H., Awazu, K. et al. Bilirubin Calculi Crushing by Laser Irradiation at a Molecular Oscillating Region Wavelength Based on Infrared Absorption Spectrum Analysis Using a Free-Electron Laser: An Experimental Study. Surg Today 31, 626–633 (2001). https://doi.org/10.1007/s005950170097
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DOI: https://doi.org/10.1007/s005950170097