The article describes a new method of treatment of pathological integumentary tissues by controlled shock-wave destruction. The controlled destruction is achieved by micro-explosions of finely dispersed particles applied to the pathological tissue surface and exposed to laser radiation. The method is implemented using laser radiation within the transparency range of biological tissues (0.6-1.1 μm) and a suspension of particles absorbing laser radiation in this range. Thermochemical reaction in the exposure zone leads to release of thermal and mechanical energy and results in destruction of biological tissues precisely in the area of application of the laser absorbing suspension. The mechanism of the shock wave effect combines several factors, including the prevailing acousto-mechanical component leading to radical explosive destruction of the superficial structures of tissues. An important distinctive feature of the method is that it allows the depth of the shock-wave effect to be controlled by varying the radiation intensity. In contrast to the well-known laser-based methods, the method suggested in this work allows the depth of the shock-wave effect to be decreased by increasing the laser radiation intensity.
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References
Neill, S. M. et al., “Guidelines for the management of lichen sclerosus,” in: British Association of Dermatologists’ Guidelines for the Management of Lichen Sclerosus (2010), pp. 12-14.
Smith, S. D. and Fischer, G., “Paediatric vulval lichen sclerosus,”Australas. J. Dermatol., No. 50 (4), 21-22 (2009).
Damirov, M. M., Laser, Cryogenic, and Radiowave Technologies in Gynecology [in Russian], Moscow (2004), pp. 17-161.
Damirov, M. M., Laser Technologies in Gynecological Practice [in Russian], Moscow (2003).
Kovalev, M. I., Low-Intensity and High-Intensity Laser Radiation in Obstetrics and Gynecology [in Russian], Moscow (2000).
Levchenko, R. G., Minkina, G. N., and Rybachenko, E. A., “Use of СО2 laser for treatment of uterine neck diseases,” in: Probl. Khir. Akush. Ginekol. Thes. 1st Congr. Russian Association of Obstetricians and Gynecologists, Moscow (1995), pp. 198-199.
Higgins, R. V., “The efficacy of laser therapy treatment of cervical intraepithelial neoplasia,” Gynecol. Oncol., 36, No. 1, 79-81 (1990).
Vaganova, E., “Combined treatment of benign diseases of the uterine neck,” Akush. Ginekol., No. 5 (2010).
Klinyshkova, T. V., Turchaninov, D. V., and Samosudov, I. B., “Evaluation of the correlation between the degree of cervical intraepithelial neoplasia and woman’s age,” Akush. Ginekol., No. 8 (2013).
Aksel’, E. M., “Statistics of malignant neoplasms of female genital organs,” Onkoginekol., No. 1, 18-23 (2012).
Savicheva, A. M., “Treatment of acute candidal vulvovaginitis: Modern trends,” Akush. Ginekol., No. 5 (2010).
Olinichenko, S. A., “Experience in treatment of urogenital candidosis,” Akush. Ginekol., No. 7-1 (2011).
Matytsina, L., Greydanus, D., and Gurkin, Y. “Vaginal microbio-coenosis and cytology of prepubertal and adolescent girls: Their role in health and disease,” Wld. J. Pediatr., 6, No. 1, 32-37 (2010).
Saliev, A. A., Increasing the Efficiency of Treatment of the Uterine Neck Pathologies Using an Infrared Diode Laser: Candidate’s dissertation [in Russian], Moscow (2012).
Stambolieva, A. V., Laser Therapy of Chronic Dystrophic Diseases of Vulva: Candidate’s dissertation [in Russian], Moscow (2009).
Van der Avoort, I. A., Tiemes, D. E., van Rossum, M. M., van der Vleuten, C. J., Massuger, L. F., and de Hullu, J. A., “Lichen sclerosus: Treatment and follow-up at the departments of gynaecology and dermatology,” J. Lower Genit. Tract Dis., 14, No. 2, 118-123 (2010).
Ezhov, V. V., Salyuk, V. A., Vtorenko, V. I., Dymkovets, V. P., and Manykin, A. A., “Contrast thermal laser therapy (CTLT) of HPV-associated pathology of the uterine neck,” Laser. Med., 15, No. 2, 80 (2011).
Vtorenko, V. I., Ezhov, V. V., Elkanova, E. E., and Salyuk, V. A., “A case of application of laser shock-wave destruction for treatment of hyperplastic dystrophy,” Laser. Med., 19, No. 2, 42-43 (2015).
Belov, S. V., Danyleiko, Yu. K., Ezhov, V. V., Lebedeva, T. P., Nefedov, S. M., Osiko, V. V., and Salyuk, V. A., “Thermal explosion of absorbing inclusions as a mechanism of destruction of biological tissues,” Dokl. Akad. Nauk, 452, No. 5, 503 (2013).
Belov, S. V., Danyleiko, Yu. K., Ezhov, V. V., Nefedov, S. M., Osiko, V. V., Salyuk, V. A., and Sidorov, V. A., “Shock-wave treatment of pathological tissues: A new method for surgical treatment of dystrophic diseases of vagina and vulva,” Dokl. Akad. Nauk, 460, No. 6, 1-5 (2015).
Belov, S. V., Danyleiko, Yu. K., Ezhov, V. V., Elkanova, E. E., and Salyuk, V. A., “Laser shock-wave destruction of the mucous membrane and skin tissues as a method of treatment of pathological processes in gynecology,” Med. Tekh., No. 6, 8-10 (2016).
Danyleiko, Yu. K. et al., “A Device for Saturating Activated Carbon with Unbound Water for Use in Laser Shock-Wave Destruction of Biological Tissues,” RF Patent No. 165 620 U1, October 27, 2016. Byul. No. 30.
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Translated from Meditsinskaya Tekhnika, Vol. 52, No. 1, Jan.-Feb., 2018, pp. 19-22.
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Belov, S.V., Danyleiko, Y.K., Ezhov, V.V. et al. Laser Shock-Wave Destruction as an Effective Method of Treatment of Pathological Integumentary Tissues. Biomed Eng 52, 27–30 (2018). https://doi.org/10.1007/s10527-018-9775-2
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DOI: https://doi.org/10.1007/s10527-018-9775-2