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Examination of colorectal cancer cases with metal allergy

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Abstract

Purpose

To report our initiatives and treatment results for patients with colorectal cancer with metal allergy.

Methods

A total of 27 patients (2.6%) with a history of metal contact dermatitis were identified among 1027 patients who underwent curative resection of colorectal cancer from 2014 to 2020. The results of the patch test, perioperative results, and postoperative colonoscopy findings were also investigated.

Results

The patch test for metal allergens and staples was performed in 21 patients (77.8%), and 13 of them (61.9%) tested positive for at least one metal allergen. Ni (38.1%), Co (28.6%), and Pd (19.0%) showed higher positive rates than other metals, and 1 patient (4.8%) tested positive for staples. Stapled anastomosis/suturing was performed as planned in 15 of 27 patients. In 10 patients, the anastomosis method was changed from stapled to hand-sewn according to the no-patch test results (60%), positivity for multiple metals (20%), positivity for staples (10%), and surgeon’s judgment (10%). No complications and abnormal colonoscopy findings were found to be associated with stapled anastomosis/suturing.

Conclusion

The patch test is useful for selecting an optimal anastomosis method for patients with suspected metal allergy.

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Data availability

The datasets generated and/or analyzed during the current study are available from the corresponding author on reasonable request.

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Acknowledgements

We thank Enago, the editing brand of Crimson Interactive Pvt. Ltd under Advance Editing B2CDrs, for editing our manuscript for English language, grammar, punctuation, and spelling.

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Authors and Affiliations

  1. Department of Coloproctological Surgery, Juntendo University Faculty of Medicine, 2-1-1 Hongo, Bunkyo-Ku, Tokyo, 113-8421, Japan

    Kosuke Mizukoshi, Yu Okazawa, Kota Amemiya, Yuki Tsuchiya, Shunsuke Motegi, Ryoichi Tsukamoto, Kumpei Honjo, Rina Takahashi, Shingo Kawano, Masaya Kawai, Shinya Munakata, Shun Ishiyama, Kiichi Sugimoto, Makoto Takahashi, Yutaka Kojima & Kazuhiro Sakamoto

  2. Department of Surgery, Kuwana City Medical Center, 3-11 Kotobuki-cho, Kuwana-shi, Mie, 511-0061, Japan

    Kosuke Mizukoshi

  3. Department of Dermatology and Allergology, Juntendo University Graduate School of Medicine, 2-1-1 Hongo, Bunkyo-Ku, Tokyo, 113-8421, Japan

    Nagisa Yoshihara & Shigaku Ikeda

Authors
  1. Kosuke Mizukoshi
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  2. Yu Okazawa
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  3. Kota Amemiya
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  16. Yutaka Kojima
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  17. Shigaku Ikeda
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  18. Kazuhiro Sakamoto
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Corresponding author

Correspondence to Kosuke Mizukoshi.

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Conflict of interest

The authors declare no conflicts of interest in association with the present study.

Ethical approval

This study was approved by the Hospital Ethics Committee of Juntendo University Hospital (19-213) and conforms to the provisions of the Declaration of Helsinki.

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Mizukoshi, K., Okazawa, Y., Amemiya, K. et al. Examination of colorectal cancer cases with metal allergy. Surg Today 53, 753–761 (2023). https://doi.org/10.1007/s00595-023-02643-7

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  • DOI: https://doi.org/10.1007/s00595-023-02643-7

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