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No inflammatory benefit obtained by single-incision laparoscopic surgery for right hemicolectomy compared with conventional laparoscopy

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Abstract

Purpose

We evaluated the perioperative inflammatory mediators in a right hemicolectomy performed with single-incision laparoscopic surgery (SILS) and traditional multi-port laparoscopic surgery (MLS) to compare the postoperative inflammatory response and feasibility of SILS with that of MLS.

Methods

In this retrospective study, we enrolled 56 consecutive colorectal cancer patients who underwent right hemicolectomy prospectively. Twenty patients underwent SILS, and 36 underwent MLS. The preoperative and postoperative levels of plasma vascular endothelial growth factor (VEGF), serum interleukin-6 (IL-6), and C-reactive protein (CRP) as well as the number of platelet cells were measured in all patients. The operation duration, number of harvested lymph nodes, length of the resected bowel, blood loss, and duration of hospital stay were also compared between the two groups.

Results

Neither SILS nor MLS had any conversion cases. The operation duration was longer for MLS than for SILS. Blood loss tended to be lower among patients who underwent SILS than among those who underwent MLS. However, the number of harvested LNs was significantly lower with SILS than with MLS. In both pre- and postoperative blood examinations, there was no marked difference in inflammatory mediators between MLS and SILS.

Conclusion

There was no systemic inflammatory advantage associated with SILS compared with MLS.

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Data availability

The patients’ clinical data used to support the findings of this study have not been made available because of the patients’ privacy.

References

  1. Chen WT, Chang SC, Chiang HC, Lo WY, Jeng LB, Wu C, Ke TW. Single-incision laparoscopic versus conventional laparoscopic right hemicolectomy: a comparison of short-term surgical results. Surg Endosc. 2011;25:1887–92.

    Article  PubMed  Google Scholar 

  2. Hiraki M, Takemasa I, Uemura M, Haraguchi N, Nishimura J, Hata T, Mizushima T, Yamamoto H, Doki Y, Mori M. Evaluation of invasiveness in single-site laparoscopic colectomy, using “the PainVision system” for quantitative analysis of pain sensation. Surg Endosc. 2014;28:3216–23.

    Article  PubMed  Google Scholar 

  3. Keshava A, Young CJ, Richardson GL, De-Loyde K. A historical comparison of single incision and conventional multiport laparoscopic right hemicolectomy. Colorectal Dis. 2013;15:e618–22.

    Article  CAS  PubMed  Google Scholar 

  4. Ramos-Valadez DI, Patel CB, Ragupathi M, Bartley Pickron T, Haas EM. Single-incision laparoscopic right hemicolectomy: safety and feasibility in a series of consecutive cases. Surg Endosc. 2010;24:2613–6.

    Article  PubMed  Google Scholar 

  5. Clavien PA, Barkun J, de Oliveira ML, Vauthey JN, Dindo D, Schulick RD, de Santibanes E, Pekolj J, Slankamenac K, Bassi C, Graf R, Vonlanthen R, Padbury R, Cameron JL, Makuuchi M. The Clavien–Dindo classification of surgical complications: five-year experience. Ann Surg. 2009;250:187–96.

    Article  Google Scholar 

  6. Esposito C. One-trocar appendectomy in pediatric surgery. Surg Endosc. 1998;12:177–8.

    Article  CAS  PubMed  Google Scholar 

  7. Navarra G, Pozza E, Occhionorelli S, Carcoforo P, Donini I. One-wound laparoscopic cholecystectomy. Br J Surg. 1997;84:695.

    Article  CAS  PubMed  Google Scholar 

  8. Piskun G, Rajpal S. Transumbilical laparoscopic cholecystectomy utilizes no incisions outside the umbilicus. J Laparoendosc Adv Surg Tech Part A. 1999;9:361–4.

    Article  CAS  Google Scholar 

  9. Chen CW, Hsiao KH, Chang YJ, Lai CW. (2013) Single-incision laparoscopic surgery using a homemade transumbilical port for synchronous colon and hepatic lesions: a case report. Surg Laparosc Endosc Percutaneous Tech 23:e164–167.

    Article  Google Scholar 

  10. Curro G, Cogliandolo A, Lazzara S, La Malfa G, Navarra G. Single-incision versus three-port conventional laparoscopic right hemicolectomy: is there any real need to go single? J Laparoendosc Adv Surg Tech Part A. 2012;22:621–4.

    Article  Google Scholar 

  11. Chew MH, Chang MH, Tan WS, Wong MT, Tang CL. Conventional laparoscopic versus single-incision laparoscopic right hemicolectomy: a case cohort comparison of short-term outcomes in 144 consecutive cases. Surg Endosc. 2013;27:471–7.

    Article  PubMed  Google Scholar 

  12. Lim SW, Kim HR, Kim YJ. Single incision laparoscopic colectomy for colorectal cancer: comparison with conventional laparoscopic colectomy. Ann Surg Treat Res. 2014;87:131–8.

    Article  PubMed  PubMed Central  Google Scholar 

  13. Mufty H, Hillewaere S, Appeltans B, Houben B. Single-incision right hemicolectomy for malignancy: a feasible technique with standard laparoscopic instrumentation. Colorectal Dis. 2012;14:e764–70.

    Article  CAS  PubMed  Google Scholar 

  14. Su Y, Wu, Kong J, Yu H, Fan Y, Tian Y. Single incision laparoscopic colorectal surgery using conventional laparoscopic instruments: initial experience with 44 cases. J Investig Surg. 2015.

  15. Chambers WM, Bicsak M, Lamparelli M, Dixon AR. Single-incision laparoscopic surgery (SILS) in complex colorectal surgery: a technique offering potential and not just cosmesis. Colorectal Dis. 2011;13:393–8.

    Article  CAS  PubMed  Google Scholar 

  16. Stage JG, Schulze S, Moller P, Overgaard H, Andersen M, Rebsdorf-Pedersen VB, Nielsen HJ. Prospective randomized study of laparoscopic versus open colonic resection for adenocarcinoma. Br J Surg. 1997;84:391–6.

    Article  CAS  PubMed  Google Scholar 

  17. Harmon GD, Senagore AJ, Kilbride MJ, Warzynski MJ. Interleukin-6 response to laparoscopic and open colectomy. Dis Colon Rectum. 1994;37:754–9.

    Article  CAS  PubMed  Google Scholar 

  18. Pascual M, Alonso S, Salvans S, Mayol X, Mojal S, Gil MJ, Grande L, Pera M. Postoperative serum vascular endothelial growth factor is an independent prognostic factor of disease free survival and overall survival in patients with non metastatic colon cancer. Am J Surg. 2018;216:255–9.

    Article  CAS  PubMed  Google Scholar 

  19. Luna RA, Nogueira DB, Varela PS, Rodrigues Neto Ede O, Norton MJ, Ribeiro Ldo C, Peixoto AM, de Mendonca YL, Bendet I, Fiorelli RA, Dolan JP. A prospective, randomized comparison of pain, inflammatory response, and short-term outcomes between single port and laparoscopic cholecystectomy. Surg Endosc. 2013;27:1254–9.

    Article  PubMed  Google Scholar 

  20. Ypsilantis P, Didilis V, Tsigalou C, Pitiakoudis M, Karakatsanis A, Margioulas A, Simopoulos C. Systemic inflammatory response after single-incision laparoscopic surgery versus standard laparoscopic approach. Surg Laparosc Endosc Percutaneous Tech. 2012;22:21–4.

    Article  Google Scholar 

  21. Froghi F, Sodergren MH, Wright VJ, Coomber R, Courtney AP, Darzi A, Paraskeva P. Single-center experience in systemic stress and short-term morbidity of single-incision cholecystectomy. Surg Innov. 2012;19:117–22.

    Article  PubMed  Google Scholar 

  22. Sohn DK, Jeong SY, Park JW, Kim JS, Hwang JH, Kim DW, Kang SB, Oh JH. Comparative study of NOTES rectosigmoidectomy in a swine model: E-NOTES vs. P-NOTES. Endoscopy. 2011;43:526–32.

    Article  CAS  PubMed  Google Scholar 

  23. Wolthuis AM, Fieuws S, Van Den Bosch A, de Buck van Overstraeten A, D’Hoore A. Randomized clinical trial of laparoscopic colectomy with or without natural-orifice specimen extraction. Br J Surg. 2015;102:630–7.

    Article  CAS  PubMed  Google Scholar 

  24. Guo J, Pasricha NP, Shenoy MM, Liu L, Mehta K, Pasricha PJ. Transgastric versus laparoendoscopic single-site peritoneoscopy in a rat model: effects on motility, inflammation, and nociception. Surg Endosc. 2012;26:747–53.

    Article  PubMed  Google Scholar 

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Authors and Affiliations

  1. Department of Gastroenterological Surgery, Nagoya City University, 1 Kawasumi, Mizuho-cho, Mizuho-ku, Nagoya, 467-8601, Japan

    Masayasu Hara, Kazuyoshi Shiga, Takeshi Yanagita, Nozomu Nakai, Nanako Ando, Korehito Takasu, Yuzo Maeda, Takaya Nagasaki, Takahisa Hirokawa, Yoichi Matsuo, Hideyuki Ishiguro, Hiroki Takahashi & Shuji Takiguchi

Authors
  1. Masayasu Hara
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  2. Kazuyoshi Shiga
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  3. Takeshi Yanagita
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  4. Nozomu Nakai
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  5. Nanako Ando
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  6. Korehito Takasu
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  7. Yuzo Maeda
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  8. Takaya Nagasaki
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  9. Takahisa Hirokawa
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  10. Yoichi Matsuo
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  11. Hideyuki Ishiguro
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  12. Hiroki Takahashi
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Correspondence to Masayasu Hara.

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Hara, M., Shiga, K., Yanagita, T. et al. No inflammatory benefit obtained by single-incision laparoscopic surgery for right hemicolectomy compared with conventional laparoscopy. Surg Today 49, 621–628 (2019). https://doi.org/10.1007/s00595-019-01777-x

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  • DOI: https://doi.org/10.1007/s00595-019-01777-x

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