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Photodynamic detection and management of intraperitoneal spreading of primary peritoneal papillary serous carcinoma in a man: report of a case

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Abstract

As a peritoneal surface malignancy, primary peritoneal papillary serous carcinoma (PPPSC) almost always occurs in women. Our search of the literature found only two previous case reports of men with PPPSC, both with very short survival. We report the case of a 63-year-old man with PPPSC, treated effectively with cytoreductive surgery and docetaxel-based hyperthermic intraperitoneal chemotherapy following six cycles of docetaxel-based laparoscopic neoadjuvant intraperitoneal and cisplatin-based systemic chemotherapy. Furthermore, we detected intraoperative intraperitoneal spreading of the tumor after the oral administration of 5-amino levulinic acid (5-ALA). The patient remains in good health without ascites 18 months after his diagnosis. Thus, primary peritoneal papillary serous carcinoma should be managed by intraperitoneal chemotherapy combined with peritonectomy procedures. Moreover, the intraoperative detection of the intraperitoneal spreading of the tumor after administering oral 5-ALA shows that this is an exciting and promising diagnostic technique, which needs to be confirmed by further studies.

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Conflict of interest

Emel Canbay and his co-authors have no conflict of interest.

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Authors and Affiliations

  1. NPO Organization to support Peritoneal Dissemination Treatment, 1-26, Harukimotomachi, Kishiwada City, Osaka, 596-0032, Japan

    Emel Canbay, Haruaki Ishibashi, Shouzou Sako, Toshiyuki Kitai & Yutaka Yonemura

  2. Department of General Surgery, Kishiwada Tokushukai Hospital, 4-27-1 Kamori-Cho, Kishiwada City, Osaka, 596-8522, Japan

    Emel Canbay, Haruaki Ishibashi, Shouzou Sako, Toshiyuki Kitai & Yutaka Yonemura

  3. Department of General Surgery, Kocaeli-Derince Education and Research Hospital, Istanbul, Kocaeli, 41900, Turkey

    Emel Canbay

  4. Department of Breast Surgery, Kyoto University, 54 Kamaracho Shogoin Sakyoku, Kyoto, 606-8507, Japan

    Toshiyuki Kitai

  5. Department of Pathology, Kishiwada Tokushukai Hospital, 4-27-1 Kamori-Cho, Kishiwada City, Osaka, 5968522, Japan

    Eisei Nishino

  6. Department of General Surgery, Kusatsu General Hospital, Yabase, Kusatsu, 1660, Japan

    Masamitsu Hirano & Akiyoshi Mizumoto

  7. Central Research Resource Branch, Cancer Research Institute, Kanazawa University, kakuma-machi, Kanazawa, 920-1192, Japan

    Yoshio Endo

  8. Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology, 4259 Nagatsuta-cho, Midori-ku, Yokohama, 226-8501, Japan

    Shun-ichiro Ogura

Authors
  1. Emel Canbay
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  2. Haruaki Ishibashi
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  3. Shouzou Sako
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  4. Toshiyuki Kitai
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  5. Eisei Nishino
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  6. Masamitsu Hirano
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  7. Akiyoshi Mizumoto
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  8. Yoshio Endo
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  9. Shun-ichiro Ogura
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  10. Yutaka Yonemura
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Correspondence to Emel Canbay.

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Canbay, E., Ishibashi, H., Sako, S. et al. Photodynamic detection and management of intraperitoneal spreading of primary peritoneal papillary serous carcinoma in a man: report of a case. Surg Today 44, 373–377 (2014). https://doi.org/10.1007/s00595-013-0500-1

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  • DOI: https://doi.org/10.1007/s00595-013-0500-1

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