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Long-term survival after resection of mass-forming type intrahepatic cholangiocarcinoma directly infiltrating the transverse colon and sequential brain metastasis: Report of a case

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Abstract

MUC1 expression in cholangiocarcinoma is considered to be correlated with patient survival. We report a case of mass-forming type intrahepatic cholangiocarcinoma (ICC) with direct infiltration of the transverse colon and sequential brain metastasis. The patient was treated by curative right hepatectomy with right hemicolectomy followed by resection of the brain metastasis; there has been no evidence of recurrence in the 7 years since the hepatic resection. Thus, surgical resection may improve the prognosis of ICC involving the adjacent organs, even with brain metastasis. Immunohistochemical staining was performed for MUC1, MUC2, and MUC5AC. Although MUC1 expression was found in the liver tumor and metastatic brain tumor, the correlation between MUC1 expression and the prognosis of this patient was unclear. To clarify the correlation between immunohistochemical characteristics and prognosis, further studies on a greater number of cases of long-term survival of mass-forming type ICC are needed.

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Authors and Affiliations

  1. Department of Surgery, Social Insurance Yokohama Central Hospital, 268 Yamashita-cho, Naka-ku, Yokohama, Kanagawa, 231-8553, Japan

    Kenji Mimatsu, Takatsugu Oida, Atsushi Kawasaki, Hisao Kano, Nobutada Fukino, Kazutoshi Kida & Youichi Kuboi

  2. Department of Surgery, Nihon University School of Medicine, Tokyo, Japan

    Sadao Amano

Authors
  1. Kenji Mimatsu
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  2. Takatsugu Oida
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  3. Atsushi Kawasaki
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  4. Hisao Kano
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  5. Nobutada Fukino
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  6. Kazutoshi Kida
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  7. Youichi Kuboi
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  8. Sadao Amano
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Mimatsu, K., Oida, T., Kawasaki, A. et al. Long-term survival after resection of mass-forming type intrahepatic cholangiocarcinoma directly infiltrating the transverse colon and sequential brain metastasis: Report of a case. Surg Today 41, 1410–1413 (2011). https://doi.org/10.1007/s00595-010-4500-0

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  • DOI: https://doi.org/10.1007/s00595-010-4500-0

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