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Current concepts in the prevention, diagnosis and treatment of fracture-related infection (FRI)

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Abstract

Fracture-related infection (FRI) is one of the most challenging complications following operative management of fractures. It can have profound implications for the patient, can be associated with considerable morbidity and often lead to impaired outcomes. There are significant healthcare-related costs. In recent years, there has been significant progress towards developing preventative strategies. Furthermore, diagnostic algorithms and management protocols have recently been reported. Lack of a strong evidence base has previously hindered efforts to implement these and develop established standards of care. There are multiple aspects of care that need to be considered and a multi-disciplinary approach is recommended. In this narrative review, we present the most up-to-date recommendations in the prevention, diagnosis and management of FRI.

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Authors and Affiliations

  1. The Royal London Limb Reconstruction Service, Royal London Hospital, Barts Health NHS Trust, London, UK

    Alexios Dimitrios Iliadis & Nima Heidari

  2. Department of Trauma & Orthopaedic Surgery, St George’s University Hospitals NHS Foundation Trust, London, UK

    Faiz Shivji & Alex Trompeter

  3. Limb Reconstruction Unit, Royal Liverpool and Broadgreen University Hospitals NHS Trust, Liverpool, UK

    Ekansh Debuka & Badri Narayan

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  1. Alexios Dimitrios Iliadis
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Iliadis, A.D., Shivji, F., Debuka, E. et al. Current concepts in the prevention, diagnosis and treatment of fracture-related infection (FRI). Eur J Orthop Surg Traumatol 31, 957–966 (2021). https://doi.org/10.1007/s00590-021-02956-8

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