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The role of intraoperative extensor digitorum brevis muscle MEPs in spinal surgery

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Abstract

Purpose

Intraoperative muscle motor evoked potentials (m-MEPs) are widely used in spinal surgery with the aim of identifying a damage to spinal cord at a reversible stage. Generally, lower limb m-MEPs are recorded from abductor hallucis [AH] and the tibialis anterior [TA]. The purpose of this work is to study an unselected population by recording the m-MEPs from TA, AH and extensor digitorum brevis (EDB), with the aim of identifying the most adjustable and stable muscles responses intraoperatively.

Methods

Transcranially electrically induced m-MEPs were intraoperative recorded in a total of 107 surgical procedures. m-MEPs were recorded by a needle electrode placed in the muscle from TA, AH and EDB muscles in the lower extremities.

Results

Overall monitorability (i.e., at least 1 Lower Limb m-MEP recordable) was 100/107 (93.5%). In the remaining 100 surgeries in 3 cases, the only muscle that could be recorded at baseline was one AH, and in other 2 the EDB. Persistence (i.e., the recordability of m-MEP from baseline to the end of surgery) was 88.7% for TA, 89.8% for AH and 93.8% for EDB.

Conclusion

In our series, EDB m-MEPs have demonstrated a recordability superior to TA and a stability similar to AH. The explanations may be different and range from changes in the excitability of the cortical motor neuron to the different sensitivity to ischemia of the spinal motor neuron. EDB can be used alternatively or can be added to TA and AH as a target muscle of the lower limb in spinal surgery.

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  1. Department of Neurosciences and Mental Health, Section of Clinical Neurophysiology, Città della Salute e della Scienza, Turin, EU, Italy

    Paolo Costa, Alessandro Borio, Sonia Marmolino, Cristina Turco, Domenico Serpella & Elena della Cerra

  2. Department of Translational Medicine, Section of Neurology, University of Piemonte Orientale, Novara, Italy

    Elia Cipriano

  3. Department of Biomedicine, Neurosciences and Advanced Diagnostic (BiND), University of Palermo, Palermo, Italy

    Salvatore Ferlisi

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Costa, P., Borio, A., Marmolino, S. et al. The role of intraoperative extensor digitorum brevis muscle MEPs in spinal surgery. Eur Spine J 32, 3360–3369 (2023). https://doi.org/10.1007/s00586-023-07811-4

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