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Health-related quality of life measured using EQ-5D in patients with lymphomas

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Abstract

Purpose

This study aimed to estimate the health preference–based index scores of the population of patients with lymphoma using the EQ-5D in China.

Methods

A cross-sectional online survey was conducted to examine the health and well-being of patients with lymphoma in China. Their health-related quality of life (HRQoL; using the EQ-5D), demographic and socioeconomic characteristics, and health conditions were assessed. The data were analyzed using Pearson’s χ2 test, analysis of variance, and binary logistic and Tobit regression models.

Results

A total of 3261 patients (sex: men = 58.5%, age: < 30 years = 9.5% and > 60 years = 24.6%) participated in the study. The mean EQ-5D-5L index and EQ-VAS scores were 0.83 and 68.8, respectively. Binary logistic regression analysis revealed that women reported more pain-related problems than men did. Unemployed participants were substantially more likely to report health problems on all the five dimensions of the EQ-5D than their employed counterparts. The Tobit regression model revealed that respondents who were older, unemployed, with low income, received chemotherapy, and with short durations reported a low index score.

Conclusion

Using the EQ-5D, the preference-based scores of different subpopulations of patients with lymphoma may support economic evaluation by promoting the simultaneous consideration of both the reasonable use of resources and satisfactory achievement of health outcomes.

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Data availability

Data may be approached by contact with correspondence author.

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Acknowledgments

The authors would like to thank House086 and all participants who helped with the study.

Author information

Authors and Affiliations

  1. The Jockey Club School of Public Health and Primary Care, The Chinese University of Hong Kong, Hong Kong SAR, China

    Richard Huan Xu, Eliza Lai-yi Wong & Dong Dong

  2. Department of Sociology, School of Social Sciences, Tsinghua University, Beijing, China

    Jun Jin

  3. Department of Medical Oncology, Sun Yat-Sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, China

    Huiqiang Huang

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  1. Richard Huan Xu
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Contributions

All authors contributed to the study conception and design. Material preparation, data collection, and analysis were performed by DD and RX. The first draft of the manuscript was written by RX. DD revised the first draft. Other authors commented on all versions of the manuscript and helped improve it. All authors read and approved the final manuscript.

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Correspondence to Dong Dong.

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Xu, R.H., Wong, E.Ly., Jin, J. et al. Health-related quality of life measured using EQ-5D in patients with lymphomas. Support Care Cancer 29, 2549–2560 (2021). https://doi.org/10.1007/s00520-020-05774-6

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  • DOI: https://doi.org/10.1007/s00520-020-05774-6

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