Abstract
Magnifying endoscopy is advantageous in detecting precancerous lesions. Our study aimed to clarify its ability to detect easily missed neoplastic lesions on the upper gastrointestinal tract. A retrospective analysis of clinical, endoscopic, and pathological data of cases undergoing gastroscopy was performed using magnifying and routine endoscopy. The detection rates of overall lesions, the ability to identify flat-type neoplastic lesions, and the easily missed neoplastic lesions were compared between the two groups. Endoscopic data from 32,367 patients was analyzed in this study. The use of magnifying endoscopy was an independent factor in identifying flat lesions (OR 2.236, 95% CI 1.969–2.540, p < 0.001), particularly type IIb lesions (OR 3.117, 95% CI 2.333–4.165, p < 0.001). For neoplastic lesions, magnifying endoscopy was also identified as having better sensitivity than routine endoscopy (sensitivity, 90.4% vs. 78.9%, p < 0.001). Similarly, magnifying endoscopy was an independent factor for identifying flat lesions (OR 2.927, 95% CI 2.365–3.621, p < 0.001), especially type IIc lesions (OR 4.415, 95% CI 3.076–6.339, p < 0.001). Magnifying endoscopy was also identified as having superior sensitivity (44.7% vs. 13.3%, p = 0.034) for early cancerous lesions. Compared to routine endoscopy, magnification endoscopy is advantageous in detecting and identifying neoplastic lesions in the upper gastrointestinal tract, especially flat neoplastic lesions and early cancers.
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Drs. Bo Jin, Xiaoliang Jin, Liang Huang, and Chunli Zhang have no conflicts of interest or financial ties to disclose. Bin Lyu has been funded by the National Natural Science Foundation of China and the Collaboration of Chinese Traditional and Modern Medicine in Gastric Cancer.
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Jin, B., Jin, X., Huang, L. et al. Magnifying endoscopy is superior at detecting easy-missed neoplastic lesions on the upper gastrointestinal tract. Surg Endosc 37, 5094–5100 (2023). https://doi.org/10.1007/s00464-023-09991-y
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DOI: https://doi.org/10.1007/s00464-023-09991-y