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Complete circular endoscopic resection using submucosal tunnel technique combined with esophageal stent placement for circumferential superficial esophageal lesions

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Abstract

Background and aims

At present, removing a circumferential superficial esophageal lesion (SEL) via en bloc resection is still a great challenge. Based on the previous success of submucosal tunneling endoscopic resection, this study aimed to evaluate the safety and effectiveness of complete circular endoscopic resection (CER) using a submucosal tunnel technique combined with esophageal stent placement for patients with circumferential SELs.

Methods

From August 2012 to June 2014, 23 patients with circumferential SELs were treated by CER using a submucosal tunnel technique combined with esophageal stent placement. The following steps were performed: (1) circular mucosa incisions were made at the anal and oral side of the lesion after marking the margin, (2) two submucosal tunnels were created from the oral to anal side using a hybrid knife, which was followed by submucosal dissection, and (3) following the completion of CER, a retrievable esophageal stent was placed to prevent postoperative stricture.

Results

CER using the submucosal tunnel technique combined with esophageal stent placement was successfully performed for all 23 cases. The complete resection and success rate were 100 %, while the mean longitudinal diameter of the lesions was 65 mm. Mediastinal emphysema, pneumothorax, and postoperative stenosis were detected in 8.7 % (2/23), 4.3 % (1/23), and 17.4 % (4/23) of the cases, respectively. Pathological diagnoses of the lesions included carcinomas (13/23) and high-grade intraepithelial neoplasias (10/23). No residual or recurrent tumors were detected in any patient during the follow-up period.

Conclusions

CER using the submucosal tunnel technique combined with esophageal stent placement seems to be a safe and effective procedure for treating patients with SELs that result in a higher en bloc resection rate with fewer or minor complications.

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Acknowledgments

This study was supported as a project of the Zhejiang province bureau of health (2013KYA226) and the TaiZhou city science and technology bureau (121ky08).

Disclosures

Ye, Zheng, Mao, Zhang, Zhou, and Zhu have no conflict of interest or financial ties to disclose.

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Authors and Affiliations

  1. Department of Gastroenterology, Taizhou Hospital of Zhejiang Province, Wenzhou Medical College, 150 Ximen Street, Linhai, 317000, Zhejiang Province, China

    Li-Ping Ye, Xin-Li Mao, Yu Zhang & Xian-Bin Zhou

  2. Department of Pathology, Taizhou Hospital of Zhejiang Province, Wenzhou Medical College, Linhai, China

    Hai-Hong Zheng

  3. Department of Medical Administration, Taizhou Hospital of Zhejiang Province, Wenzhou Medical College, Linhai, China

    Lin-Hong Zhu

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  1. Li-Ping Ye
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  2. Hai-Hong Zheng
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  3. Xin-Li Mao
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  4. Yu Zhang
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  5. Xian-Bin Zhou
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  6. Lin-Hong Zhu
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Correspondence to Yu Zhang.

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Ye, LP., Zheng, HH., Mao, XL. et al. Complete circular endoscopic resection using submucosal tunnel technique combined with esophageal stent placement for circumferential superficial esophageal lesions. Surg Endosc 30, 1078–1085 (2016). https://doi.org/10.1007/s00464-015-4301-z

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  • DOI: https://doi.org/10.1007/s00464-015-4301-z

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