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Feasibility, safety, and short-term efficacy of the laparoscopic Nissen–Hill hybrid repair

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Abstract

Background

A novel antireflux procedure combining laparoscopic Nissen fundoplication and Hill repair components was tested in 50 patients with paraesophageal hernia (PEH) and/or Barrett’s esophagus (BE) because these two groups have been found to have a high rate of recurrence with conventional repairs.

Methods

Patients with symptomatic PEH and/or non-dysplastic BE underwent repair. Quality of life (QOL) metrics, manometry, EGD, and pH testing were administered pre- and postoperatively.

Results

Fifty patients underwent repair. There was no mortality and four major complications. At 13-month follow-up, there was one (2 %) clinical recurrence, and two (4 %) asymptomatic fundus herniations. Mean DeMeester scores improved from 57.2 to 7.7 (p < 0.0001). Control of preoperative symptoms was achieved in 90 % with 6 % resumption of antisecretory medication. All QOL metrics improved significantly.

Conclusions

The hybrid Nissen–Hill repair for patients with PEH and BE appears safe and clinically effective at short-term follow-up. It is hoped that the combined structural components may reduce the rate of recurrence compared to existing repairs.

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References

  1. Lundell L, Miettinen P, Myrvold HE, Hatlebakk JG, Wallin L, Malm A, Sutherland I, Walan A, Nordic GORD Study Group (2007) Seven-year follow-up of a randomized clinical trial comparing proton-pump inhibition with surgical therapy for reflux oesophagitis. Br J Surg 94:198–203

  2. Mehta S, Bennett J, Mahon D, Rhodes M (2006) Prospective trial of laparoscopic Nissen fundoplication versus proton pump inhibitor therapy for gastroesophageal reflux disease: seven-year follow-up. J Gastrointest Surg 10:1312–1316

    Article  PubMed  Google Scholar 

  3. Mahon D, Rhodes M, Decadt B, Hindmarsh A, Lowndes R, Beckingham I, Koo B, Newcombe RG (2005) Randomized clinical trial of laparoscopic Nissen fundoplication compared with proton-pump inhibitors for treatment of chronic gastro-oesophageal reflux. Br J Surg 92:695–699

    Article  CAS  PubMed  Google Scholar 

  4. Oelschlager BK, Quiroga E, Parra JD, Cahill M, Polissar N, Pellegrini CA (2008) Long-term outcomes after laparoscopic antireflux surgery. Am J Gastroenterol 103:280–287

    Article  PubMed  Google Scholar 

  5. Dallemagne B, Kohnen L, Perretta S, Weerts J, Markiewicz S, Jehaes C (2011) Laparoscopic repair of paraesophageal hernia. Long-term follow-up reveals good clinical outcome despite high radiological recurrence rate. Ann Surg 253:291–296

    Article  PubMed  Google Scholar 

  6. Rathore MA, Andrabi SIH, Bhatti MI, Najfi SM, McMurray A (2007) Metaanalysis of recurrence after laparoscopic repair of paraesophageal hernia. JSLS 11:456–460

    PubMed Central  PubMed  Google Scholar 

  7. Jobe BA, Aye RW, Deveney CW, Domreis JS, Hill LD (2002) Laparoscopic management of giant type III hiatal hernia and short esophagus: objective follow-up at three years. J Gastrointest Surg 6:181–188

    Article  PubMed  Google Scholar 

  8. Hofstetter WL, Peters JH, DeMeester TR, Hagen JA, DeMeester SR, Crookes PF, Tsai P, Banki F, Bremner CG (2001) Long-term outcome of antireflux surgery in patients with Barrett’s esophagus. Ann Surg 234:532–538

    Article  PubMed Central  CAS  PubMed  Google Scholar 

  9. Zehetner J, DeMeester SR, Ayazi S, Costales JL, Augustin F, Oezcelik A, Lipham JC, Sohn HJ, Hagen JA, DeMeester TR (2010) Long-term follow-up after anti-reflux surgery in patients with Barrett’s esophagus. J Gastrointest Surg 14:1483–1491

    Article  PubMed  Google Scholar 

  10. Csendes A, Braghetto I, Burdiles P, Puente G, Korn O, Díaz JC, Maluenda F (1998) Long-term results of classic antireflux surgery in 152 patients with Barrett’s esophagus: clinical, radiologic, endoscopic, manometric, and acid reflux test analysis before and late after operation. Surgery 123:645–657

    Article  CAS  PubMed  Google Scholar 

  11. Pearson JB, Gray JG (1967) Oesophageal hiatus hernia: long-term results of the conventional thoracic operation. Br J Surg 54:530–533

    Article  CAS  PubMed  Google Scholar 

  12. Stylpoulos N, Rattner D (2005) The history of hiatal hernia surgery. Ann Surg 241:185–193

    Google Scholar 

  13. Luketich JD, Raja S, Fernando HC, Campbell W, Christie NA, Buenaventura PO, Weigel TL, Keenan RJ, Schauer PR (2000) Laparoscopic repair of giant paraesophageal hernia: 100 consecutive cases. Ann Surg 232:608–618

    Article  PubMed Central  CAS  PubMed  Google Scholar 

  14. Louie BE, Blitz M, Farivar AS, Orlina J, Aye RW (2011) Repair of symptomatic giant paraesophageal hernias in elderly (>70) years) patients results in improved quality of life. J Gastrointest Surg 15:389–396

    Article  PubMed  Google Scholar 

  15. Zehetner J, Demeester SR, Ayazi S, Kilday P, Augustin F, Hagen JA, Lipham JC, Sohn HJ, Demeester TR (2011) Laparoscopic versus open repair of paraesophageal hernia: the second decade. J Am Coll Surg 212:813–820

    Article  PubMed  Google Scholar 

  16. Mittal SK, Awad ZT, Tasset M, Filipi CJ, Dickason TJ, Shinno Y, Marsh RE, Tomonaga TJ, Lerner C (2000) The preoperative predictability of the short esophagus in patients with stricture or paraesophageal hernia. Surg Endosc 14:464–468

    Article  CAS  PubMed  Google Scholar 

  17. Awais O, Luketich JD (2009) Management of giant paraesophageal hernia. Minerva Chir 64:159–168

    CAS  PubMed  Google Scholar 

  18. Johnson AB, Oddsdottir M, Hunter JG (1998) Laparoscopic Collis gastroplasty and Nissen fundoplication. A new technique for the management of esophageal foreshortening. Surg Endosc 12:1055–1060

    Article  CAS  PubMed  Google Scholar 

  19. Lugaresi M, Mattioli S, Aramini B, D’Ovidio F, Di Simone MP, Perrone O (2013) The frequency of true short oesophagus in type II–IV hiatal hernia. Eur J Cardiothorac Surg 43:e30–e36

    Article  PubMed  Google Scholar 

  20. Morino M, Giaccone C, Pellegrino L, Rebecchi F (2006) Laparoscopic management of giant hiatal hernia: factors influencing long-term outcome. Surg Endosc 20:1011–1016

    Article  CAS  PubMed  Google Scholar 

  21. Oelschlager BK, Yamamoto K, Woltman T, Pellegrini C (2008) Vagotomy during hiatal hernia repair: a benign esophageal lengthening procedure. J Gastrointest Surg 12:1155–1162

    Article  PubMed  Google Scholar 

  22. Aye RW, Swanstrom LL, Kapur S, Buduhan G, Dunst CM, Knight A, Malmgren JA, Louie BE (2012) A randomized multiinstitution comparison of the laparoscopic Nissen and Hill repairs. Ann Thorac Surg 94:951–957

    Article  PubMed  Google Scholar 

  23. Qureshi AP, Aye RW, Buduhan G, Knight A, Orlina J, Farivar AS, Wagner OJ, McHugh S, Louie BE (2013) The laparoscopic Nissen–Hill hybrid: pilot study of a combined antireflux procedure. Surg Endosc 27:1945–1952

    Article  PubMed  Google Scholar 

  24. Seely AJE, Ivanovic J, Threader J, Al-Hussaini A, Al-Shehab D, Ramsay T, Gilbert S, Maziak DE, Shamji FM, Sundaresan RS (2010) Systematic classification of morbidity and mortality after thoracic surgery. Ann Thorac Surg 90:936–942

    Article  PubMed  Google Scholar 

  25. Wiklund IK, Junghard O, Grace E, Talley NJ, Kamm M, Veldhuyzen van Zanten S, Paré P, Chiba N, Leddin DS, Bigard MA, Colin R, Schoenfeld P (1998) Quality of life in reflux and dyspepsia patients. Psychometric documentation of a new disease-specific questionnaire (QOLRAD). Eur J Surg Suppl 583:41–49

    PubMed  Google Scholar 

  26. Velanovich V (2007) The development of the GERD-HRQL symptom severity instrument. Dis Esophagus 20:130–134

    Article  CAS  PubMed  Google Scholar 

  27. Dakkak M, Bennett J (1992) A new dysphagia score with objective validation. J Cliln Gastroenterol 14:99–100

    Article  CAS  Google Scholar 

  28. Aye R (2004) The hill procedure for gastroesophageal reflux. In: Yang S, Cameron DE (eds) Current therapy in thoracic and cardiovascular surgery, 1st edn. Mosby, Pennsylvania, pp 400–405

    Google Scholar 

  29. Zehetner J, Lipham JC, Ayazi S, Oezcelik A, Abate E, Chen W, Demeester SR, Sohn HJ, Banki F, Hagen JA, Dickey M, Demeester TR (2010) A simplified technique for intrathoracic stomach repair: laparoscopic fundoplication with Vicryl mesh and BioGlue crural reinforcement. Surg Endosc 24:675–679

    Article  PubMed  Google Scholar 

  30. Oelschlager BK, Pellegrini CA, Hunter J, Soper N, Brunt M, Sheppard B, Jobe B, Polissar N, Mitsumori L, Nelson J, Swanstrom L (2006) Biologic prosthesis reduces recurrence after laparoscopic paraesophageal hernia repair: a multicenter, prospective, randomized trial. Ann Surg 244:481–490

    PubMed Central  PubMed  Google Scholar 

  31. Luketich JD, Nason KS, Christie NA, Pennathur A, Jobe BA, Landreneau RJ, Schuchert MJ (2010) Outcomes after a decade of laparoscopic giant paraesophageal hernia repair. J Thorac Cardiovasc Surg 139:395–404

    Article  PubMed Central  PubMed  Google Scholar 

  32. Hatch KF, Daily MF, Christensen BJ, Glasgow RE (2004) Failed fundoplications. Am J Surg 188:786–791

    Article  PubMed  Google Scholar 

  33. Parrilla P, Martínez de Haro LF, Ortiz A, Munitiz V, Molina J, Bermejo J, Canteras M (2003) Long-term results of a randomized prospective study comparing medical and surgical treatment of Barrett’s esophagus. Ann Surg 237:291–298

    PubMed Central  PubMed  Google Scholar 

  34. Alicuben ET, Worrell SG, DeMeester SR (2014) Impact of crural relaxing incisions, Collis gastroplasty, and non-cross-linked human dermal mesh crural reinforcement on early hiatal hernia recurrence rates. J Am Coll Surg 219:988–992

    Article  PubMed  Google Scholar 

  35. Jutric Z et al (2013) A combined Nissen fundoplication with Hill gastroplasty is an alternative to Collis–Nissen repair in the treatment of short esophagus. Poster session presented at Digestive Diseases Week, 2013 May 18–21; Orlando, FL

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Acknowledgments

We would like to acknowledge the contribution of Justine Rees, the Hill Foundation and the Foundation for Surgical Fellowships.

Disclosure

Aye, Qureshi, Wilshire, Farivar, Vallières, and Louie have no conflicts of interest or financial ties to disclose.

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Correspondence to Ralph W. Aye.

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Aye, R.W., Qureshi, A.P., Wilshire, C.L. et al. Feasibility, safety, and short-term efficacy of the laparoscopic Nissen–Hill hybrid repair. Surg Endosc 30, 551–558 (2016). https://doi.org/10.1007/s00464-015-4238-2

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  • DOI: https://doi.org/10.1007/s00464-015-4238-2

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