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Standard “inject and cut” endoscopic mucosal resection technique is practical and effective in the management of superficial colorectal neoplasms

  • Endoluminal Surgery
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Abstract

Background

Standard polypectomy techniques may be contributing to ineffective eradication of colonic superficial neoplasia, an increasing number of which are nonpolypoid. We aimed to demonstrate the practicality and efficacy of the “inject and cut” endoscopic mucosal resection (EMR) technique in routine clinical practice.

Methods

Colonic EMRs performed for polypoid and nonpolypoid lesions at a tertiary institution were prospectively collected and analyzed for efficacy, and short and long-term complications.

Results

224 colonic neoplasms (143 flat, 65 sessile and 16 subpedunculated) were excised by the standard inject-and-cut method, with standard accessories. The median size of all lesions was 10 mm (range 2–50 mm) and 110 (49.2%) lesions were located in the proximal colon. Histological completeness of resection was achieved in 87% of cases. Of the lesions 77.2% were dysplastic, with 5 cases of carcinoma in situ and 18 severely dysplastic adenomas. Complications included bleeding in five cases (2.2 %) and a single case of perforation (0.4%). All complications were managed endoscopically. Median follow up at 24 ± 16 months (range 12–84 months) revealed a 7.2% local recurrence rate, all of which were subsequently eradicated by repeat EMR.

Conclusions

Standard inject-and-cut colonic EMR is practical and effective in the eradication of superficial colonic neoplasia.

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Authors and Affiliations

  1. Division of Gastroenterology, Department of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia

    Sanjiv Mahadeva

  2. Department of Gastroenterology, Leeds General Infirmary, Leeds, LS1 3EX, UK

    Bjorn J. Rembacken

Authors
  1. Sanjiv Mahadeva
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  2. Bjorn J. Rembacken
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Corresponding author

Correspondence to Bjorn J. Rembacken.

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Mahadeva, S., Rembacken, B.J. Standard “inject and cut” endoscopic mucosal resection technique is practical and effective in the management of superficial colorectal neoplasms. Surg Endosc 23, 417–422 (2009). https://doi.org/10.1007/s00464-008-9983-z

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  • DOI: https://doi.org/10.1007/s00464-008-9983-z

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