Skip to main content
SpringerLink
Log in

Small “flat adenoma” of the large bowel with special reference to its clinicopathologic features

  • Published:
Diseases of the Colon & Rectum

Abstract

Thirty-three small “flat adenomas,” not more than 1 cm in diameter, were collected from surgically and colonoscopically removed specimens, and their colonoscopic and histologic characteristics were described. There were 14 adenomas with mild atypia, five with moderate atypia, 14 with severe atypia (or focal carcinoma limited to the mucosa). The grade of atypia seems to increase with the size of lesions, and these lesions were assumed to play an important role in the adenoma-carcinoma sequence. The importance of recognizing the presence of these small “flat adenomas” in everyday practice is stressed.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Muto T, Bussey HJ, Morson BC. The evolution of cancer of the colon and rectum. Cancer 1975;36:2251–70.

    Article  CAS  PubMed  Google Scholar 

  2. Muto T, Kamiya J, Sawada T, et al. Colonoscopic polypectomy in diagnosis and treatment of early carcinoma of the large intestine. Dis Colon Rectum 1980;23:68–75.

    Article  CAS  PubMed  Google Scholar 

  3. Muto T, Kamiya J, Sawada T, Morioka Y. Morphogenesis of human colon cancer. Dis Colon Rectum 1983;26:257–62.

    Article  CAS  PubMed  Google Scholar 

  4. Nagy GS, Barratt PJ. Endoscopic polypectomy: an effective cancer prophylactic. Digestion 1977;16:265–6.

    Google Scholar 

  5. Shinya H, Wolff WI. Morphology, anatomic distribution and cancer potential of colonic polyps: an analysis of 7,000 polyps endoscopically removed. Ann Surg 1979;190:679–83.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  6. Morson BC, Dawson IM. Gastrointestinal pathology. 2nd ed. Oxford: Blackwell, 1979:164–173.

    Google Scholar 

  7. Crawford BE, Stromeyer FW. Small nonpolypoid carcinomas of the large intestine. Cancer 1983;51:1760–13.

    Article  CAS  PubMed  Google Scholar 

  8. Spratt JS Jr, Ackerman LV. Small primary adenocarcinomas of the colon and rectum. JAMA 1962;179:337–46.

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Surgery, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, 113, Tokyo, Japan

    T. Muto M.D., J. Kamiya M.D., T. Sawada M.D., F. Konishi M.D., K. Sugihara M.D., Y. Kubota M.D., M. Adachi M.D., S. Agawa M.D., Y. Saito M.D. & Y. Morioka M.D.

  2. Department of Surgery, Chulongkorn University, Chulongkorn Hospital, Bangkok, Thailand

    T. Tanprayoon M.D.

Authors
  1. T. Muto M.D.
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. J. Kamiya M.D.
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. T. Sawada M.D.
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. F. Konishi M.D.
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. K. Sugihara M.D.
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Y. Kubota M.D.
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. M. Adachi M.D.
    View author publications

    You can also search for this author in PubMed Google Scholar

  8. S. Agawa M.D.
    View author publications

    You can also search for this author in PubMed Google Scholar

  9. Y. Saito M.D.
    View author publications

    You can also search for this author in PubMed Google Scholar

  10. Y. Morioka M.D.
    View author publications

    You can also search for this author in PubMed Google Scholar

  11. T. Tanprayoon M.D.
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

This study was supported in part by a Grant-in-Aid for Scientific Research (58010005) from the Ministry of Education, Science, and Culture.

About this article

Cite this article

Muto, T., Kamiya, J., Sawada, T. et al. Small “flat adenoma” of the large bowel with special reference to its clinicopathologic features. Dis Colon Rectum 28, 847–851 (1985). https://doi.org/10.1007/BF02555490

Download citation

  • Received:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02555490

Key words

Search

Navigation