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Green synthesis of CaCO3 nanoparticles for photocatalysis and cytotoxicity

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Abstract

In this study, Gum Arabic natural polymer was used to green synthesize calcium carbonate nanoparticles (CaCO3-NPs). Synthesized CaCO3-NPs were identified using various analyses such as FTIR, XRD, FESEM, EDX, and UV–Vis. The UV spectrum of nanoparticles showed an absorption band at a wavelength of 320 nm. FTIR analysis also confirmed the synthesis of nanoparticles. XRD studies showed that CaCO3-NPs have a rhombohedral crystalline structure with space group R-3c and an average size of about 42 nm. FESEM images showed that CaCO3-NPs have cubic morphology and EDX results confirmed the presence of carbon, calcium, and oxygen elements. The synthesized CaCO3-NPs showed good photocatalytic activity to methylene blue (MB) dye degradation, which percentage degradation was 93% after 120 min. Also, the cytotoxicity of CaCO3-NPs has been examined on the normal L929 and cancer CT26 cell lines and the IC50 value was about 250 µg/mL for cancer cells.

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Acknowledgements

The technical support for this work was provided by Mashhad Kavian Institute of Higher Education and Mashhad University of Medical Sciences based on the MS thesis of Mrs. Toktam Ghadiri Soltan Meydan.

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Authors and Affiliations

  1. Department of Biology, Kavian Institute of Higher Education, Mashhad, Iran

    Toktam Ghadiri Soltan Meydan & Saeedeh Samareh Moosavi

  2. Department of Medical Biotechnology and Nanotechnology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

    Zahra Sabouri

  3. Nuclear Medicine Research Center, Mashhad University of Medical Sciences, Mashhad, Iran

    Majid Darroudi

  4. Department of Basic Medical Sciences, Neyshabur University of Medical Sciences, Neyshabur, Iran

    Majid Darroudi

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  1. Toktam Ghadiri Soltan Meydan
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  2. Saeedeh Samareh Moosavi
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  3. Zahra Sabouri
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  4. Majid Darroudi
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Contributions

TGSM: Writing—Original draft, Formal analysis, Investigation, Software. SSM: Data curation and Supervision. ZS: Formal analysis, Investigation, Software, MD: Supervision, Project administration, Validation, and Writing—review and editing.

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Correspondence to Majid Darroudi.

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Ghadiri Soltan Meydan, T., Samareh Moosavi, S., Sabouri, Z. et al. Green synthesis of CaCO3 nanoparticles for photocatalysis and cytotoxicity. Bioprocess Biosyst Eng 46, 727–734 (2023). https://doi.org/10.1007/s00449-023-02859-4

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  • DOI: https://doi.org/10.1007/s00449-023-02859-4

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