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Scaffold Name/Motif | Cell type | Sequences | Results | References |
---|---|---|---|---|
IKVAV | BMMSC | Isoleucyllysyl-valyl-alanyl-valine | Regulate cell growth and proliferation | (Li et al. 2014b) |
Hydrogels-GIPHs | BMMSC | Hydrogel-grafted IKVAV poly (lactide-co-ethylene oxide-co-fumarate) (PLEOF) | Provide cell survival and proliferation | (Zhang et al. 2014) |
Self-assembled IKVAV peptide nanofibers | Olfactory ensheathing cells (OECs) | IKVAV | Promote cell adhesion and has good biocompatibility and bioactivity | (Xu et al. 2009) |
Peptide functionalized PAMAM dendrimers | BMMSC | RGD, YIGSR or IKVAV functionalized PAMAM coated substrate | Probably promote cell adhesion | (Maturavongsadit et al. 2016) |
IKVAV-PA | PC12 NSCs DRGn | C16H31O-NH-AAAGGGEIKVAV-COOH | Promote rapid and stable adherence of PC12 cells Promote neurite outgrowth Promote the adhesion of neurons | (Tysseling-Mattiace et al. 2008; Wu et al. 2006; Zou et al. 2009) |
IKVAV-functionalized GaN | PC12 | CSRARKQAASIKVAVSADR-NH2 | Improved cell adhesion | (Jewett et al. 2012) |
Biofunctionalized peptide-based hydrogels | Spiral ganglion neurons | IKVAV-GGG-RADARADARADARADA-amide IKVAV-GGG-SIINFEKL | Attract neurite outgrowth | (Frick et al. 2016) |
IKVAV-containing peptide | NSCs | C16H31O—A3G4D2IKVAV | Induce cell growth | (Zheng et al. 2009) |
E1Y9/E1Y9-IKVAV | PC12 | Ac-EYEYKYEYKYGGGIKVAV-NH2 | Promote the neuronal differentiation | (Fukunaga et al. 2016) |
Collagen-IKVAV | DRG | IKVAV-collagen-RGD | Enhance cell proliferation | (Hosseinkhani et al. 2013) |
Silk fibroin-IKVAV | hNSCs | Silk fibroin-CSRARKQAASIKVAVSADR | Promote the neuronal differentiation, viability, and proliferation | (Sun et al. 2015) |
Short laminin peptide | hNSCs | IKVAV: Ac-Cys-Cys-Arg-Arg-Ile-LysVal-Ala-Val-Trp-Leu-Cys (CCRRIKVAVWLC) | Increase cell attachment, proliferation and differentiation into neurons | (Li et al. 2014a) |
SIKVAVS-P(HEMA-AEMA) | MSCs | SIKVAVS-P(HEMA-AEMA | Enhance cell attachment and proliferation | (Macková et al. 2016) |
IKVAVmx | NSCs | AcN-(RADA)4-GGIKVAV-CONH2) | Improve cell proliferation and neuronal differentiation | (Zhang et al. 2010) |
CQIK | Human endometrial-derived stromal cells | CQAASIKVAV | Enhance cell viability | (Tavakol et al. 2015) |
R-GSIK | NSCs | RADA4-GGSIKVAV (Ac-RADARADARADARADA-GGS-IKVAVCONH2) | Improve cell viability, proliferation, and neuronal differentiation | (Negah et al. 2016) |
References
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The online version of the original article can be found at https://doi.org/10.1007/s00441-017-2717-6
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Negah, S.S., Khooei, A., Samini, F. et al. Correction to: Laminin-derived Ile-Lys-Val-ala-Val: a promising bioactive peptide in neural tissue engineering in traumatic brain injury. Cell Tissue Res 371, 379–381 (2018). https://doi.org/10.1007/s00441-017-2739-0
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DOI: https://doi.org/10.1007/s00441-017-2739-0