Abstract.
Ultrathin sections of microfilariae of Wuchereria bancrofti embedded in hydrophilic resin were incubated with sera from patients, using antisera from asymptomatic microfilaremic patients with different microfilarial densities [1–100 microfilariae (mf)/ml, 101–500 mf/ml, >1,000 mf/ml]. All groups studied showed reactivity against relevant epitopes in all tissues of microfilariae of W. bancrofti, instead of being localized in a specific nematode region, although the number of colloidal per square micron was inversely proportional to the microfilaremia. Such results confirm data obtained by other authors and indicate a possible role for the humoral response in the mechanism for the destruction of circulating microfilariae.
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Alves, .L., Brayner, .F., Silva, .L. et al. Immunocytochemical localization of antigens recognized by asymptomatic microfilaremic patient's antisera in microfilariae of Wuchereria bancrofti . Parasitol Res 87, 1050–1055 (2001). https://doi.org/10.1007/s004360100455
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DOI: https://doi.org/10.1007/s004360100455