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Improved disease resistance after Babesia divergens vaccination

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Abstract

The efficacy of a new inactivated vaccine against Babesia divergens was evaluated by means of inoculation tests. The infection was initiated by i.v. injection of blood containing 2 × 109 living parasites into splenectomized and non-splenectomized calves. Clinical status and hematological parameters were determined. Serology examinations for antibodies against B. divergens were carried out by indirect fluorescent antibody test (IFAT). Non-vaccinated and splenectomized animals exhibited experimental infections. In vaccinated and splenectomized animals, clinical symptoms and prolonged incubation periods were observed.

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Authors and Affiliations

  1. Department of Parasitology and Zoology, Veterinary Medical University, Josef-Baumann-Gasse 1, A-1210 Vienna, Austria, , , , , , AT

    Renate Edelhofer & E. Kutzer

  2. Federal Institute for the Control of Infectious Diseases in Animals, Robert Kochgasse 17, A-2340 Mödling, Austria, , , , , , AT

    A. Kanout

  3. Second Medical Clinic, Veterinary Medical University, Josef-Baumann-Gasse 1, A-1210 Vienna, Austria, , , , , , AT

    M. Schuh

Authors
  1. Renate Edelhofer
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  2. A. Kanout
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  3. M. Schuh
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  4. E. Kutzer
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Received: 16 July 1997 / Accepted: 4 September 1997

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Edelhofer, R., Kanout, A., Schuh, M. et al. Improved disease resistance after Babesia divergens vaccination. Parasitol Res 84, 181–187 (1998). https://doi.org/10.1007/s004360050380

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  • DOI: https://doi.org/10.1007/s004360050380

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