Experimental evaluation of accuracy of radiofrequency ablation using conventional ultrasound or a third-dimension navigation tool

Abstract

Background. Successful radiofrequency-induced ablation is dependent on correct placement of the device. The ultraguide system is a three-dimensional positioning system creating an overlay of the real-time ultrasound image and a virtual image of the device.

Methods. Tumor mimics were produced by injecting an agarose/cellulose/glycerol gel into pig livers on table. The precision of device placement was evaluated either using a freehand ultrasound procedure or using the aid of the ultraguide system either by an experienced or inexperienced surgeon. Tumor mimics were ablated by a protocol yielding an ablation only discretely larger than the mimics to enhance the importance of precise positioning.

Results. The sizes of the 40 tumor mimics were: largest diameter 14.1±2.2 mm, volume 0.89±0.40 cm³. The largest diameter of ablation was 25.6±3.7 mm, the smallest diameter 21.9±2.9 mm, and the volume 7.20±2.38 cm³. The experienced surgeon was successful in 7 of 10 cases with and without the ultraguide, the inexperienced surgeon in 4 of 10 without and 7 of 10 with the ultraguide.

Conclusions. The ultraguide system may facilitate precise device placement for the less experienced surgeon. It seems worthwhile to evaluate a possible benefit of the system during placement of devices under operating room conditions.