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Branch retinal vein occlusion and vitreovascular traction: a preliminary spectral domain OCT case–control study

  • Retinal Disorders
  • Published:
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Abstract

Objective

Branch retinal vein occlusion (BRVO) typically occurs at an arteriovenous (AV) crossing site. Although the pathogenesis is unclear, vitreovascular traction might have a significant role in some BRVO cases. The purpose of present study was to determine the incidence of vitreoretinal traction at the obstruction site in patients diagnosed with BRVO.

Methods

In this prospective observational case–control study, 32 consecutive BRVO patients were studied with spectral-domain optical coherence tomography (SD-OCT) to detect the presence of vitreovascular traction or vitreous adherence at the occlusion site.

Results

SD-OCT directed to the occlusion site revealed a vitreovascular traction at this point in eight eyes (25 %). Fourteen eyes (43.75 %) were associated with an adherence of posterior hyaloids without signs of retinal traction, whereas ten eyes (31.25 %) had neither vitreoretinal adherence nor vitreous traction. Regarding either the same vessel segment of the fellow eye, none of the cases revealed vitreovascular traction in the correspondent AV crossing site; 12 cases (37.5 %) presented vitreoretinal adherence; and the remaining 20 cases (62.5 %) showed neither traction nor adhesion. Thus, vitreovascular traction in the occlusion site was significantly associated with BRVO (p = 0.024, chi-squared test). B-scan ultrasonography showed that the posterior vitreous cortex remains more frequently attached in eyes with BRVO compared to unaffected fellow eyes (p = 0.041, chi-squared test).

Conclusions

A common firm vitreous adhesion at the obstruction site is reported herein, pointing out the possible role of vitreovascular traction in the etiology of some cases of BRVO. Likewise, although not all BRVO cases can be explained by this pathogenic mechanism, an attached posterior vitreous cortex might be a cofactor in the origin of this entity.

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References

  1. Hayreh S (2005) Prevalent misconceptions about acute retinal vascular occlusive disorders. Prog Retin Eye Res 24:493–519

    Article  PubMed  Google Scholar 

  2. Charbonnel J, Glacet-Bernad A, Korobednik JF, Nyouma-Moune E, Pournaras CJ, Colin J, Coscas G, Soubrane G (2004) Management of branch retinal vein occlusion and arteriovenous adventitial sheathotomy, the possible role of posterior vitreous detachment. Graefes Arch Clin Exp Ophthalmol 242:223–228

    Article  PubMed  Google Scholar 

  3. Cahill MT, Fekrat S (2002) Arteriovenous sheathotomy for branch retinal vein occlusion. Ophthalmol Clin North Am 15:417–423

    Article  PubMed  Google Scholar 

  4. Tachi N, Hashimoto Y, Ogino N (1999) Vitrectomy for macular edema combined with retinal vein occlusion. Doc Ophthalmol 97:465–469

    Article  CAS  PubMed  Google Scholar 

  5. Stefánsson E (2009) Physiology of vitreous surgery. Graefes Arch Clin Exp Ophthalmol 247:147–163

    Article  PubMed  Google Scholar 

  6. Bertelmann T, Kičová N, Messerschmidt-Roth A, Irle S, Sekundo W, Mennel S (2011) The vitreomacular interface in retinal vein occlusion. Acta Ophthalmol 89:e327–e331

    Article  PubMed  Google Scholar 

  7. Johnson TM, Vaughn CH, Glaser BM (2006) Branch retinal vein occlusion associated with vitreoretinal traction. Can J Ophthalmol 41:600–602

    Article  PubMed  Google Scholar 

  8. Christoffersen NL, Larsen M (1999) Pathophysiology and hemodynamics of branch retinal vein occlusion. Ophthalmology 106:2054–2062

    Article  CAS  PubMed  Google Scholar 

  9. Jefferies P, Clemett R, Day T (1993) An anatomical study of retinal arteriovenous crossings and their role in the pathogenesis of retinal branch vein occlusions. Aust N Z J Ophthalmol 21:213–217

    Article  CAS  PubMed  Google Scholar 

  10. Ascaso FJ, Huerva V (2012) Vitreoretinal traction in impending branch retinal vein occlusion: a pathogenetic role? Thromb Haemost 108:208–209

    Article  CAS  PubMed  Google Scholar 

  11. Singh M, Dhir L, Kon C, Rassam S (2006) Tractional retinal break and rhegmatogenous retinal detachment consequent to branch retinal vein occlusion. Eye 20:1326–1327

    Article  CAS  PubMed  Google Scholar 

  12. Joondeph HC, Joondeph BC (1998) Posterior tractional retinal breaks complicating BRVO. Retina 8:136–140

    Article  Google Scholar 

  13. Kir E, Saatci O, Ozbek Z, Kaynak S, Ergin MH (1999) Retinal breaks and rhegmatogenous retinal detachment in association with BRVO. Ophthalmic Surg Lasers 30:285–288

    CAS  PubMed  Google Scholar 

  14. Vine AK (1984) Avulsed retinal veins without retinal breaks. Am J Ophthalmol 98:723–727

    CAS  PubMed  Google Scholar 

  15. Opremcak EM, Bruce RA (1999) Surgical decompression of branch retinal vein occlusion via arteriovenous crossing sheathotomy: a prospective review of 15 cases. Retina 19:1–5

    Article  CAS  PubMed  Google Scholar 

  16. Avci R, Inan ÜÜ, Kaderli B (2008) Evaluation of arteriovenous crossing sheathotomy for decompression of branch retinal vein occlusion. Eye 22:120–127

    Article  CAS  PubMed  Google Scholar 

  17. Horio N, Horiguchi M (2005) Effect of arteriovenous sheathotomy on retinal blood flow and macular edema in patients with branch retinal vein occlusion. Am J Ophthalmol 139:739–740

    Article  PubMed  Google Scholar 

  18. Raszewska M, Gozdek P, Cisiecki S, Michalewska Z, Michalewski J, Nawrocki J (2009) Pars plana vitrectomy with ILM peeling for macular edema secondary to retinal vein occlusion. Eur J Ophthalmol 19:1055–1062

    Google Scholar 

  19. Kurimoto M, Takagi H, Suzuma K (1999) Vitrectomy for macular edema secondary to retinal vein occlusion: evaluation by retinal thickness analyzer. Jpn J Clin Ophthalmol 53:717–720

    Google Scholar 

  20. Saika S, Tanaka T, Miyamoto T, Ohnishi Y (2001) Surgical posterior vitreous detachment combined with gas/airtamponade for treating macular edema associated with branch retinal vein occlusion: retinal tomography and visual outcome. Graefes Arch Clin Exp Ophthalmol 239:729–732

    Article  CAS  PubMed  Google Scholar 

  21. Martinez MR, Ophir A (2011) Extrafoveal traction in retinal vein occlusion using spectral domain optical coherence tomography. Graefes Arch Clin Exp Ophthalmol 249:811–820

    Article  PubMed  Google Scholar 

  22. Poort SR, Rosendaal FR, Reitsma PH, Bertina RM (1996) A common genetic variation in the 3'-untranslated region of the prothrombin gene is associated with elevated plasma prothrombin levels and an increase in venous thrombosis. Blood 88:3698–3703

    CAS  PubMed  Google Scholar 

  23. Krebs I, Brannath W, Glittenberg C, Zeiler F, Sebag J, Binder S (2007) Posterior vitreomacular adhesion: a potential risk factor for exudative age related macular degeneration? Am J Ophthalmol 144:741–746

    Article  PubMed  Google Scholar 

  24. Schulze S, Hoerle S, Mennel S, Kroll P (2008) Vitreomacular traction and exudative age-related macular degeneration. Acta Ophthalmol 86:470–481

    Article  PubMed  Google Scholar 

  25. Robison CD, Krebs I, Binder S, Barbazetto IA, Kotsolis AI, Yannuzzi LA, Sadun AA, Sebag J (2009) Vitreomacular adhesion in active and end-stage age-related macular degeneration. Am J Ophthalmol 148:79–82

    Article  PubMed  Google Scholar 

  26. Stefánsson E, Geirsdóttir Á, Sigurdsson H (2011) Metabolic physiology in age related macular degeneration. Prog Ret Eye Res 30:72–80

    Article  Google Scholar 

  27. Muraoka Y, Tsujikawa A, Murakami T, Ogino K, Kumagai K, Miyamoto K, Uji A, Yoshimura N (2013) Morphologic and functional changes in retinal vessels associated with branch retinal vein occlusion. Ophthalmology 120:91–99

    Article  PubMed  Google Scholar 

  28. Kičová N, Bertelmann T, Irle S, Sekundo W, Mennel S (2012) Evaluation of a posterior vitreous detachment: a comparison of biomicroscopy, B-scan ultrasonography and optical coherence tomography to surgical findings with chromodissection. Acta Ophthalmol 90:e264–e268

    Article  PubMed  Google Scholar 

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Conflict of interest

The authors confirm that they were fully involved in the study and preparation of the manuscript and that the material within has not been and will not be submitted for publication elsewhere. Moreover, as far as the authors know there is no conflict of interest in this manuscript.

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Authors and Affiliations

  1. Department of Ophthalmology, “Lozano Blesa” University Clinic Hospital, San Juan Bosco 15, ES-50009, Zaragoza, Spain

    Francisco J. Ascaso, Esteban Padgett, Esther Núñez, Laura Villén & José A. Cristóbal

  2. Aragon Health Sciences Institute, Zaragoza, Spain

    Francisco J. Ascaso

  3. University of Zaragoza, Zaragoza, Spain

    Francisco J. Ascaso & José A. Cristóbal

  4. Department of Ophthalmology, Poznań City Hospital, Poznań, Poland

    Andrzej Grzybowski

  5. Department of Ophthalmology, University of Warmia and Mazury, Olsztyn, Poland

    Andrzej Grzybowski

Authors
  1. Francisco J. Ascaso
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  2. Esteban Padgett
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  3. Esther Núñez
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  4. Laura Villén
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  5. Andrzej Grzybowski
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  6. José A. Cristóbal
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Correspondence to Francisco J. Ascaso.

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Ascaso, F.J., Padgett, E., Núñez, E. et al. Branch retinal vein occlusion and vitreovascular traction: a preliminary spectral domain OCT case–control study. Graefes Arch Clin Exp Ophthalmol 252, 375–381 (2014). https://doi.org/10.1007/s00417-013-2463-8

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  • DOI: https://doi.org/10.1007/s00417-013-2463-8

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