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Frequent spontaneous eyeblink activity associated with reduced conjunctival surface (trigeminal nerve) tactile sensitivity

  • Neuro-ophthalmology
  • Published:
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Abstract

Background

A number of recent studies have reported high spontaneous eyeblink rate (SEBR) values in apparently normal subjects, but the reasons for this are unclear.

Methods

An assessment was made of SEBR, in 60 educated adult male subjects aged between 22 and 40 years, over a period of 5 min in silence. Half of the subjects were classified as having frequent eyeblink activity. All subjects also had their corneal and conjunctival touch (tactile) sensitivity assessed with a Cochet-Bonnet aesthesiometer immediately after the video recording of SEBR.

Results

SEBR ranged from 4.6 to 43.5 (mean 18.6) eyeblinks/min. The SEBR was 26.8 ± 6.0 eyeblinks/min for those with frequent eyeblink activity as compared to just 10.3 ± 3.5 eyeblinks/min for those with normal eyeblink activity (p < 0.001). There was no difference in palpebral aperture or exposed ocular surface area between the two groups. The average central corneal sensitivity was only marginally different between the two groups (56.8 ± 2.8 mm vs 58.5 ± 2.3 mm) but the conjunctival threshold sensitivity was substantially different (at 23.8 ± 4.3 mm vs 28.5 ± 3.5 mm; p < 0.001). SEBR was inversely correlated with the conjunctival sensitivity in those with frequent eyeblink activity (p < 0.001).

Conclusions

Our study provides a clue as to the mechanism of inhibition of spontaneous eyeblink activity, namely that a certain level of ocular surface (conjunctival) sensitivity is required to keep SEBR low.

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Acknowledgements

The authors would like to thank Dr. Emil Oblak, Joanna Ross, Julie McWhirter, Hashmi Gor and Elaine Milne for assistance in collection of some of the eyeblink and sensitivity data in pilot studies.

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Authors and Affiliations

  1. Department of Vision Sciences, Glasgow-Caledonian University, Cowcaddens Road, Glasgow, G4 OBA, Scotland

    Michael J. Doughty, Taher Naase & Norman F. Button

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  1. Michael J. Doughty
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  2. Taher Naase
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  3. Norman F. Button
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Correspondence to Michael J. Doughty.

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Doughty, M.J., Naase, T. & Button, N.F. Frequent spontaneous eyeblink activity associated with reduced conjunctival surface (trigeminal nerve) tactile sensitivity. Graefes Arch Clin Exp Ophthalmol 247, 939–946 (2009). https://doi.org/10.1007/s00417-008-1028-8

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  • DOI: https://doi.org/10.1007/s00417-008-1028-8

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