Abstract
Background
This report describes a case of central serous chorioretinopathy following intravitreal triamcinolone acetonide injection.
Methods
A 42-year-old man presented with a 4-month history of decreased visual acuity (0.4) in his left eye. The left eye demonstrated macular edema due to branch retinal vein occlusion. Triamcinolone acetonide 4 mg/ 0.1 mL was injected intravitreally to treat the macular edema.
Results
Pigmentary retinal discoloration, retinal pigment epithelium leakage and a slight neurosensorial detachment with cystoid macular edema at the temporal macula were present prior to intravitreal triamcinolone injection. Three weeks after injection, visual acuity had decreased to 0.2 and metamorphopsies appeared in the left eye. A sharply demarcated serous macular elevation and a progressively increasing hyperfluorescence of the pre-existing leakage point led to the diagnosis of “exacerbation of the pre-existing asymptomatic central serous chorioretinopathy” following intravitreal triamcinolone injection. Macular elevation spontaneously resolved by the 4th month post-injection. At the 6th month, the patient experienced recurrence of a small serous detachment at the temporal macula.
Conclusion
Central serous chorioretinopathy exacerbation may arise as a complication of intravitreal triamcinolone acetonide injection.
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References
Bouzas EA, Karadimas P, Pournaras CJ (2002) Central serous chorioretinopathy and glucocorticoids. Surv Ophthalmol 47:431–448 doi:10.1016/S0039-6257(02)00338-7
Costen MT, Olson JA (2000) Central serous chorioretinopathy may be a manifestation of the primary antiphospholipid syndrome. Br J Ophthalmol 84:667 doi:10.1136/bjo.84.6.667
Imasawa M, Ohshiro T, Gotoh T, Imai M, Iijima H (2005) Central serous chorioretinopathy following vitrectomy with intravitreal triamcinolone acetonide for diabetic macular oedema. Acta Ophthalmol Scand 83:132–133 doi:10.1111/j.1600-0420.2005.00379.x
Jonas JB (2005) Intravitreal triamcinolone acetonide for treatment of intraocular edematous and neovascular diseases. Acta Ophthalmol Scand 83:645–663 doi:10.1111/j.1600-0420.2005.00592.x
Jonas JB, Kamppeter BA (2005) Intravitreal triamcinolone acetonide and central serous chorioretinopathy. Br J Ophthalmol 89:386–387 doi:10.1136/bjo.2004.054247
Karacorlu M, Ozdemir H, Karacorlu SA (2005) Resolution of serous macular detachment after intravitreal triamcinolone acetonide treatment of patients with branch retinal vein occlusion. Retina 25:856–860 doi:10.1097/00006982-200510000-00007
Karadimas P, Bouzas EA (2004) Glucocorticoid use represents a risk factor for central serous chorioretinopathy: a prospective, case-control study. Graefes Arch Clin Exp Ophthalmol 242:800–802 doi:10.1007/s00417-004-0885-z
Leo-Kottler B, Klein R, Berg PA, Zrenner E (1998) Ocular symptoms in association with antiphospholipid antibodies. Graefes Arch Clin Exp Ophthalmol 236:658–668 doi:10.1007/s004170050138
Yamaguchi Y, Otani T, Kishi S (2006) Serous macular detachment in branch retinal vein occlusion. Retina 26:1029–1033 doi:10.1097/01.iae.0000254893.94013.16
Wang M, Munch IC, Hasler PW, Prünte C, Larsen M (2008) Central serous chorioretinopathy. Acta Ophthalmol (Copenh) 86:126–145 doi:10.1111/j.1600-0420.2007.00889.x
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Kocabora, M.S., Durmaz, S. & Kandemir, N. Exacerbation of central serous chorioretinopathy following intravitreal triamcinolone injection. Graefes Arch Clin Exp Ophthalmol 246, 1783–1786 (2008). https://doi.org/10.1007/s00417-008-0932-2
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DOI: https://doi.org/10.1007/s00417-008-0932-2