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Epilepsy during the Middle Ages, the Renaissance and the Enlightenment

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Abstract

The purpose of this study was to pinpoint the views on epilepsy as a disease and symptom during medieval times and the Renaissance. A thorough study of texts, medical books and reports along with a review of the available literature in PubMed was undertaken. With the exception of some early Byzantine doctors in the East and some of the representatives of Arab medicine, scientific views and observations on epilepsy in the West were overrun by the domination of the Catholic Church. This led to the formulation of superstitious views of the disease; epileptics were considered possessed and, therefore, only religious methods could possibly cure it. Near the end of the fourteenth century, physicians were emancipated from Catholic intervention. The Renaissance is marked by a plethora of new treatises on epilepsy regarding the mechanisms of epileptic convulsions, the connection with various clinical conditions such as tumors and venereal diseases and the collection of interesting cases.

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Notes

  1. Hegemonicon (ηγεμονικόν) comes from the word hegemon, meaning sovereign. Writers use this term to define the part of the brain that controls bodily functions.

References

  1. Agios Tychonas. http://www.agiostychonas.com/agios_tychonas.shtml. Accessed 24 May 2009

  2. Ali Ibn Abbas (1523) Theorica, IX, 6. In: Liber totius medicine necessaria continens quem sapientissimus Haly Filius Abbas …. edidit, regique inscripsit, unde et regalis, dispositionis nomen assumpsit. Lyon, fol. 103

  3. Abulcasim (1778) De chirurgia. In: Channing J (ed) De chirurgia, vol I. Oxford, p 31

  4. Abulcasim (1519) Liber theoricae nec non practicae Alsaharavii, qui vulgo Acararius dicitur. Augsburg, fol. 34

  5. Aegina, Paulus of (1921–1924) Paulus Aeginita, III, 14. In: Heiberg IL (ed) Paulus Aegenita, 2 vols. Teubner, Leipzig-Berlin, 120–122, p 156

  6. Africanus C (1536–1539) De communibus medico etc. IX, 7 vol 2. In: Opera. Basel, p 247

  7. Africanus C (1515) Pantegni, lib. V. In: Omnia opera ysaac in hoc volumine contenta: cum quibusdam aliis opusculis. Lyon, practicae c. 17, fol. 99

  8. Aretaeus (1856) On epilepsy, Chapter V, on the causes and symptoms of acute diseases, Book I. In: Adams F (ed) The extant work of Aretaeus the Cappadocian. The Sydenham society, London, pp 244–246

    Google Scholar 

  9. Aurelianus C (1950) Morbis chronici, I, 4. In: Drabkin IE (ed) On acute diseases and on chronic diseases. The University Chicago Press, Chicago, par. 62

  10. Avicenna (1999) The canon of medicine. Kazi, Chicago

    Google Scholar 

  11. Beyerstein BL (1988) Neuropathology and the legacy of spiritual possession. Skeptical Inquirer 12.3:248–262

    Google Scholar 

  12. Brain SR (1959) William Harvey, neurologist. Brit Med J 2:899

    Article  CAS  PubMed  Google Scholar 

  13. Budrys V (2007) Neurology in Holy Scripture. Eur J Neurol 14:e1–e6

    Article  CAS  PubMed  Google Scholar 

  14. Caesalpinus A (1593) Daemonum investigation peripatetica. In: Quastionum peripateticarum lib. V. Daemonum investigatio peripatetica, Quaestionum medicarum libri Ii, De medicament. facultatibus lib. II. c. 1, fol. 145 C

  15. d’Orsi G, Tinuper P (2006) “I heard voices…”: from semiology, a historical review, and a new hypothesis on the presumed epilepsy of Joan of Arc. Epilepsy Behav 9:152–157

    Article  PubMed  Google Scholar 

  16. Dolger FJ (1933) Der Ausschluss der Besessenen (Epileptiker) von Oblation und Kommunion nach der Synode von Elvira. Antike und Christentum 4:110–129

    Google Scholar 

  17. Donatus M (1613) De historia medica mirabili, liber II. In: De historia medica mirabili libri sex, opera et studio Gregori Horsti. Francofurti ad Moenum, c. 4, p 145

  18. Drelincurtius C (1682) Experimenta anatomica. Ernestum Gottfried Heyseum, Leiden

    Google Scholar 

  19. Economou NT, Lascaratos J (2005) The Byzantine physicians on epilepsy. J Hist Neurosci 14:346–352

    Article  CAS  PubMed  Google Scholar 

  20. Erastus T (1581) Comitis Montani Vincentini novi medicorum censoris quinque librorum de morbis nuper editorum viva anatome. Basel, p 195

  21. Felix C (1879) De medicina, c. 71. In: Rose V (ed) De medicina. Leipzig, pp 168–169

  22. Fernelius J (1577) De abditis rerum causis. In: Universa medicina. Francofurti ad Moenum, II, c. 15, p 87

  23. Forestus P (1634) Observatorium, liber X. In: Observatorium et curationum medicinalium ac chircurgicarum opera omnia. Frankfurt, observ. 56, p 385

  24. Gaddesden, John of (1595) Rosa Anglica. In: Ioannis Anglici Praxis Medica, rosa anglica dicta, recens edita opera ac studio clar. V. Doct. Philippi Schopffi, Medici Physici Durlacensis, 2 vols. Typis Michaëlis Mangeri, Augsburg, p 40

  25. Galen (1821–1833) De locis affectis, vol 8. In: Kuhn CG (ed) Opera Omnia. Leipzig, p 194

  26. Glisson F (1677) Tractatus de ventriculo et intestinis. London, c. 8, 6, p 161

  27. Gordon, Bernard of (1542) Lilium medicinae. In: Omnium aegritudinum a vertice ad calcem, opus praeclariss. quod lilium medicinae appellatur. Paris, fol. 119

  28. St. Hildegard (1903) Causae et cureae, 13–16. In: Kaiser P (ed) Hildegardis Causae et cureae. Teubner, Leipzig, p 156

    Google Scholar 

  29. Hippocrate (1849) De la maladie sacrée, Livre 6. In: Littré E (ed) Oeuvres complètes d’Hippocrate. Baillière J-B, Paris, p 364

    Google Scholar 

  30. Hunter R, MacAlpine I (1957) William Harvey: his neurological and psychiatric observation. J Hist Med 12:126

    CAS  Google Scholar 

  31. Kerler DH (1905) Die Patronate der Heiligen. Kerler, Ulm

    Google Scholar 

  32. Kluger G, Kudernatsch V (2009) St. Valentine—patron saint of epilepsy: illustrating the semiology of seizures over the course of six centuries. Epilepsy Behav 14:219–225

    Article  PubMed  Google Scholar 

  33. Le Pois C (1733) de Epilepsia, Consilium, chap 7. In: Boerhaave H (ed) Caroli Pisonis….selectiorum observationum et consiliorum… liber singularis. Leiden, p 115

  34. Lemnius L (1658) The Secret Miracles of Nature, II, 3. In: The secret miracles of nature. London, p 93

  35. Makris G (1995) Zur Epilepsie in Byzanz. Byzantinische Zeitschrift 88:363–404

    Article  Google Scholar 

  36. Marcus Marci a Kronland (1678) Liturgia mentis seu disceptatio medica, philosophica et optica de natura epilepsiae illius ortu et causis. Regensburg

  37. Martin A (1922) Warum galten Epilepsie und Geisteskrankheit (Frenesis) als ansteckend? Deutsche Zeitschrift fur Nervenheilkunde 75:103–110

    Article  Google Scholar 

  38. Mc Henry LC (1969) The Middle Ages and the Renaissance. In: Mc Henry LC (ed) Garrison’s history of neurology. Charles C. Thomas, Springfield, p 30

    Google Scholar 

  39. Mesue J (1623) Grabadin, idest compendii secretorum medicamentorum liber secundus. In: Ioannis Mesuae damasceni medici clarissimi opera de medicamentorum purgantium delectu, catigatione & usu, libri duo. […] et Ioannis Costaei annotationes Luntas…. Venice, summa 3, c. 26; fol. 208

  40. Nonnus T (1794–1795) Theophanis Nonni epitome de curatione morborum, 2 vols. Gothae, Amsterdam

  41. Paracelsus (1922–1933) Elf Traktat von Ursprung, Ursachen, Zeichen und Kur einzelner Krankheiten, vol 1. In: Sämtliche Werke, 1. Abteilung, medizinische naturwissenschaftlische und philosophische Schriften, herausgegebn von K. Sudfhoff 14 vols. Oldenbourg, Munich-Berlin, pp 142–152, “Vom fallend”

  42. Paracelsus (1922–1933) Von den hinfallenden siechtagen, vol 8. In: Sämtliche Werke, 1. Abteilung, medizinische naturwissenschaftlische und philosophische Schriften, herausgegebn von K. Sudfhoff 14 vols. Oldenbourg, Munich-Berlin, p 280

  43. Paracelsus (1922-1933) Von den hinfallenden siechtagen, vol 8. In: Sämtliche Werke, 1. Abteilung, medizinische naturwissenschaftlische und philosophische Schriften, herausgegebn von K. Sudfhoff 14 vols. Oldenbourg, Munich-Berlin, pp 281-284

  44. Quercetanus J (1609) Tetras gravissimorm totius capitis affectuum. Marburg, p 114

  45. Rhodius J (1676) Observatorium medicinalium centuriae, obs. 55. In: Observatorium medicinalium centuriae tres. Frankfurt, p 33

  46. Rulandus M (1580) Curatinum etc. centuria sexta, centuria 9, curatio 99. In: Curationum empiricarum et historicarum in certis locis et notis personis optime expertarum, et rite probatarum, centuria prima (secunda) emendatius impressa. Basel, p 157

  47. Rulandus M (1580) Curatinum etc. centuria sexta, curatio 100. In: Curationum empiricarum et historicarum in certis locis et notis personis optime expertarum, et rite probatarum, centuria prima (secunda) emendatius impressa. Basel, pp 132–133

  48. Savonarola JM (1547) Practica maior. In: Practica maior. Venice, tract. 6, c. 1, rubrica 20; fol. 71

  49. Serapion J (1530) Platearii Practica Brevis. In: Necessarium ac perutile opus totius medicine practice profundissimi ac antiquissimi Arabis domini Joannis filii Serapionis… Practica etiam brevis Domini Joannis Platearij Salernitani ultisiima, fol. 172

  50. Stahl GE (1831–1833) Theoria medica vera. Pathologia, vol 2. In: Choulant L (ed) Theoria medica vera. Leipzig, pp 263–264

  51. Steeghius G (1606) Medicina practica, liber VII. In: Ars medica. Frankfurt, c. 3, p 323

  52. Sylvius (1635) Prax. med. In: Opera medica. Geneva, pp II, c. 20, 83; p 319

  53. Taxil J (1602) Traicté de l’êpilepsie, maladie vulgairement appelée au pays de Provence la gouttete aux petits enfants, c. 17

  54. Taxil J (1602) Traicté de l’êpilepsie, maladie vulgairement appelée au pays de Provence la gouttete aux petits enfants, p 22 f

  55. Temkin O (1942) A medieval translation of Rhaze’s clinical observations. Bull Hist Med 12:102–117

    Google Scholar 

  56. Temkin O (1971) The Middle Ages. In: Temkin O (ed) The falling sickness: a history of epilepsy from the Greeks to the beginnings of modern neurology. The John Hopkins University Press Ltd, London, p 105

    Google Scholar 

  57. Temkin O (1971) The Middle Ages. In: Temkin O (ed) The falling sickness: a history of epilepsy from the Greeks to the beginnings of modern neurology. The John Hopkins University Press Ltd, London, p 95

    Google Scholar 

  58. Tharanta, Valescus De (1523) Philonium, I. In: Philonium: Aureum ac perutile opus practice medicine operarum dantibus quod Philonium appellatur, consumatissimi medici domini Valesci de Tharanta. Lucamontanus, Venice, p 18; fol. 16

  59. Tissot (1770) Traité de l’épilepsie. Faisant le tome troisième du Traité des nerfs et de leurs maladies. Paris, p 117

  60. Tralles, Alexander of (1878) Alexander von Tralles, vol I. In: von Puschmann T (ed) Alexander von Tralles, Original-Text und Ubersetzung. Vienna, I, 15, p 575

  61. Tralles, Alexander of (1556) Medici libri duoedecim, vol I, chap 5. In: Petrum H (ed) Alexander Tralliani medici libri duodecim. Gunther Andernach, Basel

  62. Vilanova, Arnald of (1585) Breviarium. In: Opera Omnia. Basel, I, 22, col. 1071

  63. Vilanova, Arnald of (1585) Breviarium. In: Opera Omnia. Basel, I, c13, col. 1074

  64. Vilanova, Arnald of (1585) De Epilepsia. In: Opera Omnia. Basel, c. 1, col. 1603

  65. Wepfer JJ (1679) Cicutae aquaticae historia et noxae. Basel

  66. Willis T (1682) De morbis convulsivis. In: Opera omnia. Amsterdam, c. 1, pp 13–14

  67. Willis T (1684) Of Convulsive diseases, chap 1. In: Dr. Willi’s practice of physick, being the whole works of the renowned and famous physician. London, p 5

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Correspondence to Emmanouil Magiorkinis.

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Diamantis, A., Sidiropoulou, K. & Magiorkinis, E. Epilepsy during the Middle Ages, the Renaissance and the Enlightenment. J Neurol 257, 691–698 (2010). https://doi.org/10.1007/s00415-009-5433-7

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