Abstract
The allele frequency and sequence structure of the STR locus D12S1090 were investigated in 598 Flemish individuals. The locus shows a complex organisation with repetitions of GATA interrupted by TA and other tetra- and pentanucleotide blocks. No deviation from Hardy-Weinberg equilibrium was observed. The extensive polymorphism makes it a powerful tool for identity as well as paternity testing and even permits differentiation of closely related populations, such as Flemish and Germans. D12S1090 seems to be one of the most informative STRs, however, as seen in other highly variable STRs, the observed mutation frequency of 5.1 × 10–3, is relatively high.
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Received: 5 October 2000 / Accepted: 2 April 2001
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Mertens, G., Mommers, N., Boutrand, L. et al. Flemish population data and sequence structure of the hypervariable tetranucleotide repeat locus D12S1090. Int J Leg Med 115, 40–44 (2001). https://doi.org/10.1007/s004140100227
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DOI: https://doi.org/10.1007/s004140100227