Skip to main content

Advertisement

Log in

Third molar maturity index (I3M) for assessing age of majority in northern Chinese population

  • Original Article
  • Published:
International Journal of Legal Medicine Aims and scope Submit manuscript

Abstract

In many countries, assessment of legal age, also known as age of majority, has become increasingly important over the years. In China, individuals older than 18 years of age have full capacity regarding civil conduct and can be tried as an adult for criminal charges. Therefore, from a legal point of view, it is crucial to determine whether an individual is an adult. The developmental degree of the third molar is widely recognized as a suitable site for age estimation in late adolescence. This article uses the third molar maturity index (I3M) with a cutoff value of I3M = 0.08, which was established by Cameriere et al. in 2008, to distinguish whether an individual is a minor or an adult (≥ 18 years of age) in a northern Chinese population. A total of 840 digital orthopantomograms (OPTs) from 420 male and 420 female northern Chinese subjects aged 12 to 25 years were evaluated. It was found that an increase in I3M corresponded to a decrease in chronological age. In our study, I3M = 0.10 showed better accuracy in age discrimination in both men and women. This threshold also resulted in high sensitivity (0.929 and 0.809) and specificity (0.940 and 0.973) in males and females, respectively. The proportion of correctly classified subjects was 0.917 (95% CI, 0.898 to 0.935) in total, 0.938 (95% CI, 0.915 to 0.961) in male and 0.895 (95% CI, 0.866 to 0.925) in female subjects. Bayes post-test probabilities were 0.967 (95% CI, 0.947 to 0.986) in males and 0.983 (95% CI, 0.966 to 0.998) in females. These differences in threshold values between Chinese and Caucasian populations might be because the development of third molars is delayed in the Chinese population compared to the Caucasian population. In conclusion, I3M might be a useful method in legal and forensic practices to determine ages in late adolescence in northern Chinese individuals. However, a specific population should be tested before I3M is used for legal age estimation.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3
Fig. 4

Similar content being viewed by others

References

  1. Abbing HD (2011) Age determination of unaccompanied asylum seeking minors in the European Union: a health law perspective. Eur J Health Law 18:11–25

    Article  Google Scholar 

  2. AlQahtani S, Kawthar A, AlAraik A, AlShalan A (2017) Third molar cut-off value in assessing the legal age of 18 in Saudi population. Forensic Sci Int 272:64–67

    Article  Google Scholar 

  3. Balla SB, Galic I, P K, Vanin S, De Luca S, Cameriere R (2017) Validation of third molar maturity index (I3M) for discrimination of juvenile/adult status in South Indian population. J Forensic Legal Med 49:2–7

    Article  Google Scholar 

  4. Cameriere R, Ferrante L, De Angelis D, Scarpino F, Galli F (2008) The comparison between measurement of open apices of third molars and Demirjian stages to test chronological age of over 18 year olds in living subjects. Int J Legal Med 122:493–497

    Article  CAS  Google Scholar 

  5. Cameriere R, Pacifici A, Viva S, Carbone D, Pacifici L, Polimeni A (2014) Adult or not? Accuracy of Cameriere’s cut-off value for third molar in assessing 18 years of age for legal purposes. Minerva Stomatol 63:283–294

    PubMed  CAS  Google Scholar 

  6. Cameriere R, Santoro V, Roca R, Lozito P, Introna F, Cingolani M, Galic I, Ferrante L (2014) Assessment of legal adult age of 18 by measurement of open apices of the third molars: study on the Albanian sample. Forensic Sci Int 245:205 e201–205 e205

    Article  Google Scholar 

  7. Cavric J, Galic I, Vodanovic M, Brkic H, Gregov J, Viva S, Rey L, Cameriere R (2016) Third molar maturity index (I3M) for assessing age of majority in a black African population in Botswana. Int J Legal Med 130:1109–1120

    Article  Google Scholar 

  8. Cavric J, Vodanovic M, Marusic A, Galic I (2016) Time of mineralization of permanent teeth in children and adolescents in Gaborone, Botswana. Ann Anat 203:24–32

    Article  Google Scholar 

  9. Dardouri AAK, Cameriere R, De Luca S, Vanin S (2016) Third molar maturity index by measurements of open apices in a Libyan sample of living subjects. Forensic Sci Int 267:230 e231–230 e236

    Article  Google Scholar 

  10. De Luca S, Aguilar L, Rivera M, Palacio LA, Riccomi G, Bestetti F, Cameriere R (2016) Accuracy of cut-off value by measurement of third molar index: study of a Colombian sample. Forensic Sci Int 261(160):e161–e165

    Google Scholar 

  11. De Luca S, Biagi R, Begnoni G, Farronato G, Cingolani M, Merelli V, Ferrante L, Cameriere R (2014) Accuracy of Cameriere’s cut-off value for third molar in assessing 18 years of age. Forensic Sci Int 235(102):e101–e106

    Google Scholar 

  12. Deitos AR, Costa C, Michel-Crosato E, Galic I, Cameriere R, Biazevic MG (2015) Age estimation among Brazilians: younger or older than 18? J Forensic Legal Med 33:111–115

    Article  Google Scholar 

  13. Franklin D, Karkhanis S, Flavel A, Collini F, DeLuca S, Cameriere R (2016) Accuracy of a cut-off value based on the third molar index: validation in an Australian population. Forensic Sci Int 266:575 e571–575 e576

    Article  Google Scholar 

  14. Galic I, Lauc T, Brkic H, Vodanovic M, Galic E, Biazevic MG, Brakus I, Badrov J, Cameriere R (2015) Cameriere’s third molar maturity index in assessing age of majority. Forensic Sci Int 252(191):e191–e195

    Google Scholar 

  15. Gelbrich B, Lessig R, Lehmann M, Dannhauer KH, Gelbrich G (2010) Age selection in reference samples. Rechtsmedizin 20:459–463

    Article  Google Scholar 

  16. Gulsahi A, De Luca S, Cehreli SB, Tirali RE, Cameriere R (2016) Accuracy of the third molar index for assessing the legal majority of 18 years in Turkish population. Forensic Sci Int 266(584):e581–e586

    Google Scholar 

  17. Gulsahi A, Tirali RE, Cehreli SB, De Luca S, Ferrante L, Cameriere R (2015) The reliability of Cameriere’s method in Turkish children: a preliminary report. Forensic Sci Int 249:319.e1-5

    Article  Google Scholar 

  18. Guo YC, Lin XW, Zhang WT, Yan CX, Pan F, Yan TL, Li JP, Chen T, Schmeling A, Zhou H (2015) Chronology of third molar mineralization in a northern Chinese population. Rechtsmedizin 25:34–39

    Article  CAS  Google Scholar 

  19. Harris EF (2007) Mineralization of the mandibular third molar: a study of American blacks and whites. Am J Phys Anthropol 132:98–109

    Article  Google Scholar 

  20. King M (1992) Practical Statistics for Medical Research—Altman, Dg. J Psychosom Res 36:603–603

    Google Scholar 

  21. Knell B, Ruhstaller P, Prieels F, Schmeling A (2009) Dental age diagnostics by means of radiographical evaluation of the growth stages of lower wisdom teeth. Int J Legal Med 123:465–469

    Article  CAS  Google Scholar 

  22. Lewis JM, Senn DR (2010) Dental age estimation utilizing third molar development: a review of principles, methods, and population studies used in the United States. Forensic Sci Int 201:79–83

    Article  Google Scholar 

  23. Li G, Ren J, Zhao S, Liu Y, Li N, Wu W, Yuan S, Wang H (2012) Dental age estimation from the developmental stage of the third molars in western Chinese population. Forensic Sci Int 219:158–164

    Article  Google Scholar 

  24. Liu Y, Geng K, Chu Y, Xu M, Zha L (2018) Third molar mineralization in relation to chronologic age estimation of the Han in central southern China. Int J Legal Med. https://doi.org/10.1007/s00414-018-1804-x

    Article  Google Scholar 

  25. Olze A, Schmeling A, Taniguchi M, Maeda H, van Niekerk P, Wernecke KD, Geserick G (2004) Forensic age estimation in living subjects: the ethnic factor in wisdom tooth mineralization. Int J Legal Med 118:170–173

    Article  Google Scholar 

  26. Quispe Lizarbe RJ, Solis Adrianzen C, Quezada-Marquez MM, Galic I, Cameriere R (2017) Demirjian’s stages and Cameriere’s third molar maturity index to estimate legal adult age in Peruvian population. Leg Med (Tokyo) 25:59–65

    Article  Google Scholar 

  27. Rai B, Kaur J, Cingolani M, Ferrante L, Cameriere R (2010) Age estimation in children by measurement of open apices in teeth: an Indian formula. Int J Legal Med 124:237–241

    Article  Google Scholar 

  28. Schmeling A, Geserick G, Reisinger W, Olze A (2007) Age estimation. Forensic Sci Int 165:178–181

    Article  CAS  Google Scholar 

  29. Schmeling A, Grundmann C, Fuhrmann A, Kaatsch HJ, Knell B, Ramsthaler F, Reisinger W, Riepert T, Ritz-Timme S, Rosing FW, Rotzscher K, Geserick G (2008) Criteria for age estimation in living individuals. Int J Legal Med 122:457–460

    Article  CAS  Google Scholar 

  30. Schmeling A, Reisinger W, Geserick G, Olze A (2006) Age estimation of unaccompanied minors. Part I General considerations. Forensic Sci Int 159(Suppl 1):S61–S64

    Article  Google Scholar 

  31. Thevissen PW, Fieuws S, Willems G (2010) Human third molars development: comparison of 9 country specific populations. Forensic Sci Int 201:102–105

    Article  CAS  Google Scholar 

  32. Zelic K, Galic I, Nedeljkovic N, Jakovljevic A, Milosevic O, Djuric M, Cameriere R (2016) Accuracy of Cameriere’s third molar maturity index in assessing legal adulthood on Serbian population. Forensic Sci Int 259:127–132

    Article  Google Scholar 

Download references

Acknowledgements

The authors would like to thank Dr. Jian-min Yang of the College of Stomatology, Xi’an Jiaotong University for his generous assistance in improving the use of English in the manuscript. This work was supported by the National Natural Science Foundation of China (No. 81701869 and No. 81571859), the Fundamental Research Funds for the Central Universities (No. xjj2017168), Shanghai Key Laboratory of Forensic Medicine (No. 17DZ2273200), and Shanghai Forensic Service Platform (No. 16DZ2290900).

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Yu-cheng Guo.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Chu, G., Wang, Yh., Li, Mj. et al. Third molar maturity index (I3M) for assessing age of majority in northern Chinese population. Int J Legal Med 132, 1759–1768 (2018). https://doi.org/10.1007/s00414-018-1907-4

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00414-018-1907-4

Keywords

Navigation