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Genetic analysis of 12 X-chromosome STRs in Western Mediterranean populations

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Abstract

Haplotype and allele frequencies of 12 X-STRs included in the Investigator Argus X-12 kit are reported for 255 individuals, representing four Western Mediterranean populations: Valencia (eastern mainland Spain) and the Balearic Islands (Majorca, Minorca, and Ibiza). Ibiza shows the lowest intra-population variability and the highest level of linkage disequilibrium together with an important genetic distance with regard to the geographically close populations, which is consistent with the historical evidence for long-term demographic isolation and its different matrilineal background.

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Acknowledgments

This work was partially supported by grant AAEE133/09 from the Direcció General de R + D + I (Comunitat autònoma de les Illes Balears) and European Regional Development Fund (ERDF).

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Authors and Affiliations

  1. Institut Universitari d’Investigació en Ciències de la Salut (IUNICS) i Laboratori de Genètica, Departament de Biologia, Universitat de les Illes Balears, Carretera de Valldemossa, km 7.5, 07122, Palma de Mallorca, Illes Balears, Spain

    J. F. Ferragut, K. Bentayebi, J. A. Castro, C. Ramon & A. Picornell

  2. Biochemistry and Immunology laboratory-Forensic Unit, Mohammed V Agdal University, Faculty of Sciences, Avenue Ibn Batouta Agdal, BP, 1014, Rabat, Morocco

    K. Bentayebi

Authors
  1. J. F. Ferragut
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  2. K. Bentayebi
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  3. J. A. Castro
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  4. C. Ramon
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  5. A. Picornell
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Corresponding author

Correspondence to A. Picornell.

Electronic supplementary material

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Supplementary Figure 1

Multidimensional scaling analysis (MDS) based on Reynolds genetic distances calculated between populations. African populations are represented by circular points, European populations by square dots and Balearic and Valencia populations are labelled with stars. (PDF 212 kb)

Supplementary Table 1

Allele frequencies of 12X-STR in 350 chromosomes (Majorca (MAJ): 41 men and 22 women; Minorca (MIN): 39 men and 25 women; Ibiza (IBI): 41 males and 20 women; Valencia (VAL): 39 men and 28 women) (PDF 47 kb)

Supplementary Table 2

X-chromosome haplotypes of four linked STR trios in 121 males from Balearic Islands (41 from Majorca, 39 from Minorca and 41 from Ibiza) and 39 males from Valencia populations. More common haplotypes (5%) are labelled with * (PDF 337 kb)

Supplementary Table 3

Linkage disequilibrium inside the 4 Linkage Groups (LG) in Mallorca, Minorca, Ibiza and Valencia populations. In bold, significant p-values after Bonferroni correction (PDF 135 kb)

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Ferragut, J.F., Bentayebi, K., Castro, J.A. et al. Genetic analysis of 12 X-chromosome STRs in Western Mediterranean populations. Int J Legal Med 129, 253–255 (2015). https://doi.org/10.1007/s00414-014-1071-4

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  • DOI: https://doi.org/10.1007/s00414-014-1071-4

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