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Allele frequencies of 11 X-chromosomal loci in a population sample from Ghana

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Abstract

Eleven X-chromosomal short tandem repeats (STRs) from two multiplex PCR approaches (DXS6807, DXS8378, DXS7132, DXS6800, DXS9898, DXS7424, DXS101, DXS7133, HPRTB, DXS8377, and DXS7423), located in four different X-chromosomal linkage groups, were typed in a population sample from Ghana, Africa. After genotyping unrelated men (129) and women (114) from the Ashanti population, forensic efficiency parameters such as polymorphism information content and mean exclusion chance were calculated. A deviation from the Hardy–Weinberg equilibrium could not be found. The investigation of 11 father–daughter and seven mother–son meioses revealed no mutations in any STR analyzed. Our data were compared with European, African-American, and Asian populations from the literature.

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Authors and Affiliations

  1. Institute of Forensic Medicine, University Hospital Essen, Hufelandstr. 55, 45122, Essen, Germany

    Micaela Poetsch & Daniela El-Mostaqim

  2. Landeskriminalamt Nordrhein-Westfalen, Düsseldorf, Germany

    Frank Tschentscher

  3. Department of Community Health, School of Medical Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana

    Edmund N. L. Browne

  4. Department of Molecular Medicine, Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany

    Christian Timmann & Rolf D. Horstmann

  5. Institute of Legal Medicine, University of Schleswig-Holstein, Campus Kiel, Kiel, Germany

    Nicole von Wurmb-Schwark

Authors
  1. Micaela Poetsch
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  2. Daniela El-Mostaqim
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  3. Frank Tschentscher
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  4. Edmund N. L. Browne
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  5. Christian Timmann
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  6. Rolf D. Horstmann
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  7. Nicole von Wurmb-Schwark
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Correspondence to Micaela Poetsch.

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Poetsch, M., El-Mostaqim, D., Tschentscher, F. et al. Allele frequencies of 11 X-chromosomal loci in a population sample from Ghana. Int J Legal Med 123, 81–83 (2009). https://doi.org/10.1007/s00414-008-0251-5

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  • DOI: https://doi.org/10.1007/s00414-008-0251-5

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