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Genetic structure of a Cuban population based on nine short tandem repeat loci

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Abstract

Cuba is a multiethnic and multiracial society. Here we describe the genetic variation of a sample of the Cuban population, which include the three most common racial groups, Caucasians, Negroids and Mestizos, by means of a set of nine microsatellites (HUMTH01, HUMTPOX, HUMCFS1PO, HUMVWA, HUMFESFPS, HUMF13A, HUMF13B, HUMLPL and HUMHPRTB). The analysis presented here indicates that these STR loci are highly informative for forensic purposes. The genetic data on the major racial groups is in good agreement with current demographic tendencies and with historic events that took place during the formation of the Cuban population.

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References

  • Albeza MV, Picornell A, Acreche N, Tomas C, Castro JA, Ramon MM (2002) Genetic variability at 14 STR loci in the Puna population of northwestern Argentina. Int J Leg Med 116:126–132

    Google Scholar 

  • Andres MI, Prieto V, Flores IC, Sanz P (1996) Population genetics of three STRs: TH01, CSF1PO and TPOX in Southern Spain. Adv Forensic Haemog 6:489–491

    Google Scholar 

  • Bell B, Nievas P, Abecia E, Martínez-Jarreta B, Hinojal R, Martinez-Cordero A (2000) Population genetics of the STR loci HUMCSF1PO, HUMF13A01, HUMFES/FPS and D12S391 in Asturias (Northern Spain). Forensic Sci Int 113:21–23

    Google Scholar 

  • Budowle B, Moretti TR (1999) Genotype profiles for six population groups at the 13 CODIS short tandem repeat core loci and other PCR-based loci. Forensic Sci Commun 1(2)

  • Budowle B, Monson KL, Chakraborty R (1996) Estimating minimum allele frequencies for DNA profile frequency estimates for PCR-based loci. Int J Leg Med 108:173–176

    Google Scholar 

  • Crespillo M, Luque JA, Fernández R, Ramírez E, García P, Valverde JL (1997) Allele frequency distributions of 13 PCR-based systems in a population from North-east Spain. Int J Leg Med 110:223–225

    Google Scholar 

  • Gene M, Carracedo A, Huguet E, Pérez-Pérez A, Moreno P (1998) Population genetics of the D12S391, CSF1PO and TPOX loci in Catalonia (Northeast Spain). Int J Leg Med 111:52–54

    Google Scholar 

  • Gene M, Moreno P, Borrego N, Pique E, Brandt C, Mas J, Luna M, Corbella J, Huguet E (2001) The Bubi population of Equatorial Guinea characterized by HUMTH01, HUMVWA31A, HUMCSF1PO, HUMTPOX, D3S1358, D8S1179, D18S51 and D19S253 STR polymorphisms. Int J Leg Med 114:298–300

    Google Scholar 

  • Goncalves R, Jesús J, Fernandes AT, Brehm A (2002) Genetic profile of a multi-ethnic population from Guiné-Bissau (west African coast) using the new PowerPlex 16 System kit. Forensic Sci Int 129:78–80

    Google Scholar 

  • Goudet J, Raymond M, De Meeüs T, Rousset F (1996) Testing differentiation in diploid populations. Genetics 144:1933–1940

    CAS  PubMed  Google Scholar 

  • Guanche J (1996) Componentes Etnicos de la Nación Cubana. Fundación Fernando Ortiz, Ediciones Unión, Ciudad de La Habana

  • Hidalgo PC, Cabrera J, Castellanos T, López N, González O, Villar M, Bauer I (1999). Abnormal hemoglobins and racial admixture in Villa Clara province. Cuban J Hum Genet 1(2)

  • Huguet E, Borrego N, Pinheiro MF, Luna M, Corbella J, Mas J, Gené M, Moreno P (1998) Annobon Island population (Equatorial Guinea) characterised by five VNTRs-PCR polymorphisms. Prog Forensic Genet 7:329–331

    Google Scholar 

  • Lewis PO, Zaykin D (2001) Genetic data analysis: computer program for the analysis of allelic data. Version 1.0 (d16c). Free program distributed by the authors over the Internet from http://lewis.eeb.uconn.edu/lewishome/software.html

  • Lleonart R, Riego E, Sainz de la Pena MV, Bacallao K, Amaro F, Santiesteban M, Blanco M, Currenti H, Puentes A, Rolo F, Herrera L, de la Fuente (2000) Forensic identification of skeletal remains from members of Ernesto Che Guevara’s guerrillas in Bolivia based on DNA typing. Int J Leg Med 113(2):98–101

    Google Scholar 

  • Lleonart R, Carpio Y, Sainz de la Peña MV, Santiesteban M, Rodríguez G, Ferreira R, Amaro F, Riego E, Bacallao K, Blanco M (2003) Genetic structure of the contemporary Cuban population for nine STR loci. Int Congr Ser 1239:147–148

    Google Scholar 

  • Martínez-Jarreta B, Diaz Roche P, Budowle B, Abecia E, Castellano M, Casalod Y (1998) Pyrenean population data on 3 tetrameric short tandem repeat loci—HUMTH01, TPOX and CSF1PO-derived using a STR multiplex system. Prog Forensic Genet 7:312–314

    Google Scholar 

  • Martínez-Labarga C, Rickards O, Scacchi R, Corbo RM, Biondi G, Peña JA, Varas de Vieira C, Guevara AEB, Mesa Saturino MS, De Stefano GF (1999) Genetic population structure of two African-Ecuadorian communities of Esmeraldas. Am J Phys Anthropol 109:159–174

    Google Scholar 

  • Minch E, MICROSAT, http://hpgl.stanford.edu/projects/microsat/) (Stanford University)

  • Pérez-Lezaun A, Calafell F, Clarimón J, Bosch E, Mateu E, Gusmao L, Amorim A, Benchemsi N, Bertranpetit J (2000) Allele frequencies of 13 short tandem repeats in population samples from the Iberian Peninsula and northern Africa. Int J Leg Med 113:208–214

    Google Scholar 

  • Raymond M, Rousset F (1995a) GENEPOP (version 1.2): population genetics software for exact tests and ecumenicism. J Heredity 86:248–249

    Google Scholar 

  • Raymond M, Rousset F (1995b) An exact test for population differentiation. Evolution 49:1280–1283

    Google Scholar 

  • Reynolds J, Weir BS, Cockerham CC (1983) Estimation of the coancestry coefficient: basis for a short-term genetic distance. Genetics, 105:767–779

    Google Scholar 

  • Rivero de la Calle, M (1984) Antropología de la Población Adulta Cubana. Editorial Científico-Técnica, La Habana

  • Szibor R, Krawczak M, Hering S, Edelmann J, Kuhlisch E, Krause D (2003) Use of X-linked markers for forensic purposes. Int J Leg Med 117:67–74

    Google Scholar 

  • Tofanelli S, Boschi I, Bertoneri S, Coia V, Taglioli L, Franceschi MG, Destro-Bisol G, Pascali V, Paoli G (2003) Variation at 16 STR loci in Rwandans (Hutu) and implications on profile frequency estimation in Bantu-speakers. Int J Leg Med 17:121–126

    Google Scholar 

  • Walsh PS, Metzger DA, Higuchi R (1991) Chelex 100 as a medium for simple extraction of DNA for PCR-based typing from forensic material. BioTechniques 10:506

    Google Scholar 

  • Weir S (1996) Genetic Data Analysis II. Sinauer Associates, Sunderland, MA, USA

    Google Scholar 

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Correspondence to Ricardo Lleonart.

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Carpio, Y., Sainz de la Peña, M.V., Santiesteban, M. et al. Genetic structure of a Cuban population based on nine short tandem repeat loci. Int J Legal Med 119, 137–141 (2005). https://doi.org/10.1007/s00414-005-0522-3

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