Abstract
This study introduces a new experimental set-up for particle detection within the nasal airways and describes intranasal deposition of particles at various regions of the nasal cavity and the nasopharynx. During respiration of an aerosol of starch particles the nondeposited particles in the air were detected in 11 volunteers by a transnasally placed suction probe at numerous sites of the nasal cavity and nasopharynx. Another, identical suction probe measured the initial number of inhaled particles at the nostril. The two suction probes were connected to two identical laser particle counters and allowed calculation of particle deposition. Particles 1–3 μm in size were deposited to about 60% within the entire nasal cavity, whereas most of the particles 4–30 μm in size were deposited within the entire nasal cavity. Between 80% and 90% of the particles retained in the nasal cavity were deposited at the anterior nasal segment. Studies on deposition of various drugs within the nasal cavity using this experimental set-up are conceivable.
Similar content being viewed by others
Author information
Authors and Affiliations
Additional information
Received: 29 May 2000 / Accepted: 10 August 2000
Rights and permissions
About this article
Cite this article
Keck, T., Leiacker, R., Klotz, M. et al. Detection of particles within the nasal airways during respiration. European Archives of Oto-Rhino-Laryngology 257, 493–497 (2000). https://doi.org/10.1007/s004050000283
Issue Date:
DOI: https://doi.org/10.1007/s004050000283