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A single centre’s experience of 23 cases of total rhinectomy for the treatment of squamous cell carcinoma involving the nasal vestibule

  • Head and Neck
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European Archives of Oto-Rhino-Laryngology Aims and scope Submit manuscript

Abstract

Purpose

This study aims to analyse the oncological outcomes of total rhinectomy (TR) for squamous cell carcinomas (SCCs) involving the nasal vestibule, and to identify prognostic factors for disease recurrence.

Methods

A retrospective single-centre study was conducted between September 2003 and February 2021 including all patients who underwent a TR for a SCC involving the nasal vestibule.

Results

23 patients were included in the study. Tumours originated from the anterior septum (n = 12), vestibule (n = 8) or skin (n = 3). Six TRs (26.1%) were salvage procedures, after primary radiotherapy or partial rhinectomy. Seven patients had a concurrent neck dissection and 17 patients (73.9%) received adjuvant treatment (14 patients had radiotherapy and 3 had chemoradiotherapy). After a median follow-up of 32 months, six patients (26.1%) presented with tumour recurrence. Three patients (13%) had nodal-only recurrence. The estimated 5-year overall survival, disease-free survival and disease-specific survival were 67.5%, 66.3% and 80.7%, respectively. Positive excision margins were a predictive factor for tumour recurrence (p = 0.0401).

Conclusion

For SCCs involving the nasal vestibule that are not amenable to limited surgical resection, TR along with adjuvant radiotherapy provide good oncological outcomes and should be considered the main treatment option.

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Availability of data

The data that support the findings of this study are available from the corresponding author upon reasonable request.

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Funding

The authors received no funding for the publication of this study.

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Authors and Affiliations

  1. Department of Ear, Nose and Throat Surgery, Sheffield Teaching Hospitals Foundation Trust, Royal Hallamshire Hospital, Glossop Rd, Broomhall, Sheffield, S10 2JF, UK

    Emilien Chabrillac, Ashish Talawdekar, Sara Sionis, Nigel Beasley & Richard Jackson

  2. Department of Surgery, University Cancer Institute Toulouse-Oncopole, Toulouse, France

    Emilien Chabrillac

  3. Department of Oncology, Weston Park Hospital, Sheffield, UK

    Satya Garikipati

  4. Department of Oral and Maxillo-Facial Surgery, Sheffield Teaching Hospitals Foundation Trust, Sheffield, UK

    Iain Varley

Authors
  1. Emilien Chabrillac
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  2. Ashish Talawdekar
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  3. Satya Garikipati
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  4. Iain Varley
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  5. Sara Sionis
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  6. Nigel Beasley
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  7. Richard Jackson
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Contributions

Emilien Chabrillac designed the work; Emilien Chabrillac acquired and analysed data; Emilien Chabrillac, Richard Jackson, Ashish Talawdekar, Iain Varley, Satya Garikipati, Sara Sionis and Nigel Beasley drafted, revised and approved the manuscript; Emilien Chabrillac, Richard Jackson, Ashish Talawdekar, Iain Varley, Satya Garikipati, Sara Sionis and Nigel Beasley agree to be accountable for all aspects of the work.

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Correspondence to Emilien Chabrillac.

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Chabrillac, E., Talawdekar, A., Garikipati, S. et al. A single centre’s experience of 23 cases of total rhinectomy for the treatment of squamous cell carcinoma involving the nasal vestibule. Eur Arch Otorhinolaryngol 279, 2069–2075 (2022). https://doi.org/10.1007/s00405-021-06972-6

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  • DOI: https://doi.org/10.1007/s00405-021-06972-6

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