Abstract
To assess sexual functioning in male and female partners before and after nasal continuous positive airway pressure (CPAP) therapy in men with obstructive sleep apnea (OSA). Twenty-one male patients with moderate to severe OSA and erectile dysfunction, and their female partner, were recruited into this prospective study. Males diagnosed with OSA were treated with nasal CPAP therapy for 12 weeks. Women were assessed for sexual functioning using the Female Sexual Function Index (FSFI), and for mood status using the Beck Depression Inventory (BDI), before and after their male partner underwent nasal CPAP therapy. Sexual functioning was assessed in men using the International Index of Erectile Function (IIEF), before and after nasal CPAP therapy. After nasal CPAP therapy for OSA in men, IIEF scores were significantly higher than pre-treatment scores. Total pre- and post-treatment IIEF scores (mean ± standard deviation) were 50.28 ± 15.88 and 65.42 ± 7.47, respectively, P < 0.01. Pre- and post-treatment FSFI scores in women were 21.54 ± 6.62 and 29.94 ± 3.76, respectively, P < 0.01. Pre- and post-treatment BDI scores in women were 14.61 ± 9.69 and 12.42 ± 8.92, respectively, P < 0.01. Following treatment of men with OSA, our data indicate benefits for nasal CPAP therapy on sexual functioning in both the male and female partners. Moreover, our findings indicate that improved sexual function in women after their male partner underwent nasal CPAP also had psychological benefits.
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References
Friedman M, Maley A, Kelley K et al (2011) Impact of nasal obstruction on obstructive sleep apnea. Otolaryngol Head Neck Surg 144:1000–1004
Hoekema A, Stel AL, Stegenga B et al (2007) Sexual function and obstructive sleep apnea-hypopnea: a randomized clinical trial evaluating the effects of oral-appliance and continuous positive airway pressure therapy. J Sex Med 4:1153–1162
Perimenis P, Karkoulias K, Konstantinopoulos A et al (2007) The impact of long-term conventional treatment for overlap syndrome (obstructive sleep apnea and chronic obstructive pulmonary disease) on concurrent erectile dysfunction. Respir Med 101:210–216
Fanfulla F, Malaguti S, Montagna T et al (2000) Erectile dysfunction in men with obstructive sleep apnea: an early sign of nerve involvement. Sleep 23:775–780
Bai Q, Xu QQ, Jiang H, Zhang WL, Wang XH, Zhu JC (2004) Prevalence and risk factors of erectile dysfunction in three cities of China: a community-based study. Asian J Androl 6:343–348
Fisher WA, Rosen RC, Eardley I, Sand M, Goldstein I (2005) Sexual experience of female partners of men with erectile dysfunction: the female experience of men’s attitudes to life events and sexuality (FEMALES) study. J Sex Med 2:675–684
Rosen R, Brown C, Heiman J et al (2000) The Female Sexual Function Index (FSFI): a multi- dimensional self-report instrument for the assessment of female sexual function. J Sex Marital Ther 26:191–208
Rosen RC, Riley A, Wagner G, Osterloh IH, Kirkpatrick J, Mishra A (1997) The international index of erectile function (IIEF): a multidimensional scale for assessment of erectile dysfunction. Urology 49:822–830
Beebe D, Finer E, Holmbeck GN (1996) Low-end specificity of four depression measures: findings and suggestions for the research use of depression tests. J Pers Assess 67:272–284
Meston N, Davies RJ, Mullins R, Jenkinson C, Wass JA, Stradling JR (2003) Endocrine effects of nasal continuous positive airway pressure in male patients with obstructive sleep apnoea. J Intern Med 254:447–454
Bratel T, Wennlund A, Carlstrom K (1999) Pituitary reactivity, androgens and catecholamines in obstructive sleep apnoea. Effects of continuous positive airway pressure treatment (CPAP). Respir Med 93:1–7
Macrea MM, Martin TJ, Zagrean L (2010) Infertility and obstructive sleep apnea: the effect of continuous positive airway pressure therapy on serum prolactin levels. Sleep Breath 14:253–257
Taskin U, Yigit O, Acioglu E, Aricigil M, Toktas G, Guzelhan Y (2010) Erectile dysfunction in severe sleep apnea patients and response to CPAP. Int J Impot Res 22:134–139
Margel D, Tal R, Livne PM, Pillar G (2005) Predictors of erectile function improvement in obstructive sleep apnea patients with long-term CPAP treatment. Int J Impot Res 17:186–190
Karacan I, Karatas M (1995) Erectile dysfunction in sleep apnea and response to CPAP. J Sex Marital Ther 21:239–247
Pressman MR, DiPhillipo MA, Kendrick JI, Conroy K, Fry JM (1986) Problems in the interpretation of nocturnal penile tumescence studies: disruption of sleep by occult sleep disorders. J Urol 136:595–598
Hirshkowitz M, Karacan I, Arcasoy MO, Acik G, Narter EM, Williams RL (1990) Prevalence of sleep apnea in men with erectile dysfunction. Urology 36:232–234
Budweiser S, Luigart R, Jörres RA et al (2013) Long-term changes of sexual function in men with obstructive sleep apnea after initiation of continuous positive airway pressure. J Sex Med 10:524–531
Ip MS, Lam B, Chan LY et al (2000) Circulating nitric oxide is suppressed in obstructive sleep apnea and is reversed by nasal continuous positive airway pressure. Am J Respir Crit Care Med 162:2166–2171
Phillips BG, Narkiewicz K, Pesek CA, Haynes WG, Dyken ME, Somers VK (1999) Effects of obstructive sleep apnea on endothelin-1 and blood pressure. J Hypertens 17:61–66
Verratti V, Falone S, Fanò G et al (2011) Effects of hypoxia on nocturnal erection quality: a case repot from the Manaslu expedition. J Sex Med 8:2386–2390
Khafagy AH, Khafagy AH (2012) Treatment of obstructive sleep apnoea as a therapeutic modality for associated erectile dysfunction. Int J Clin Pract 66:1204–1208
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Acar, M., Kaya, C., Catli, T. et al. Effects of nasal continuous positive airway pressure therapy on partners’ sexual lives. Eur Arch Otorhinolaryngol 273, 133–137 (2016). https://doi.org/10.1007/s00405-015-3546-4
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DOI: https://doi.org/10.1007/s00405-015-3546-4