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Obstetrical outcomes following laparoscopy during pregnancy: a retrospective case–control study

  • General Gynecology
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Abstract

Purpose

To evaluate pregnancy outcome of patients who undergo laparoscopy during pregnancy.

Methods

A retrospective case–control study, conducted in a single university-affiliated tertiary care medical center, comparing pregnancy outcomes of women who underwent laparoscopy during pregnancy to women without operations during pregnancy. The study group (n = 232) included all pregnant women who underwent a single laparoscopic surgery during pregnancy (4–28 weeks of gestation) which culminated in delivery between 2006 and 2017; this study group was matched to a control group (n = 463) without surgical intervention during pregnancy, in a 2:1 ratio by maternal age, parity, and multiple gestation.

Results

The main pregnancy outcomes included preterm birth, cesarean section, small for gestational age (≤ 10 percentile), and Apgar score of less than 7 in 5 min. Laparoscopy during pregnancy was associated with an increased risk for cesarean section (32.3% vs. 24.6%, adjusted OR = 1.9, CI 1.2–3.1, p = 0.011). We found no difference between the groups with regard to other outcomes, including rates of preterm birth (12.1% vs. 10.4%, adjusted OR = 1.3, CI 0.64–2.72, p = 0.451). In a subgroup analysis of the study group, various perioperative parameters such as operation duration, hospitalization length, and others, did not correlate with adverse pregnancy outcome.

Conclusions

Laparoscopy during pregnancy may be associated with an increased rate of cesarean section. We did not find an increase in any other pregnancy or neonatal complication. Different perioperative parameters did not appear to predict adverse pregnancy outcome.

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Funding

The research was not supported.

Author information

Authors and Affiliations

  1. Department of Obstetrics and Gynecology, Lis Maternity Hospital, Tel Aviv Sourasky Medical Center, 6 Weizman Street, 6423906, Tel Aviv, Israel

    Neta Solomon, Miriam Warshaviak, Ariel Gimple, Eran Ashwal, Ishai Levin & Tamar Tzur

Authors
  1. Neta Solomon
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  2. Miriam Warshaviak
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  3. Ariel Gimple
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  4. Eran Ashwal
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  5. Ishai Levin
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  6. Tamar Tzur
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Contributions

All authors contributed to the study conception and design. TT developed the project. NS and TT wrote the first draft of the manuscript. Data collection was performed by NS, MW, and AG. Manuscript editing was conducted by EA and IL. All authors commented on previous versions of the manuscript. All authors read and approved the final manuscript. NS: project development, data collection, data analysis, manuscript writing. MW: data collection. AG: Data collection. EA: manuscript editing. IL: manuscript editing. TT: project development, manuscript writing, and editing.

Corresponding author

Correspondence to Neta Solomon.

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Conflict of interest

We declare that we have no conflict of interest.

Ethics approval

The study was approved by the Tel- Aviv Sourasky Medical Center institutional review board on 26/7/2019, protocol number 0365–17 TLV.

Consent to participate

The study was approved by the Institutional Review Board at Tel- Aviv Sourasky Medical Center (approval number 0365–17 TLV). The review board waived the need for individual written informed consent due to our retrospective study design. The data were analyzed anonymously.

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The manuscript is original and has not published elsewhere in any form or language (partially or in full).

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All data and materials support the published claims and comply with field standards.

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Solomon, N., Warshaviak, M., Gimple, A. et al. Obstetrical outcomes following laparoscopy during pregnancy: a retrospective case–control study. Arch Gynecol Obstet 302, 1421–1427 (2020). https://doi.org/10.1007/s00404-020-05767-0

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  • DOI: https://doi.org/10.1007/s00404-020-05767-0

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