Skip to main content
SpringerLink
Log in

Treatment of iron deficiency and iron deficiency anemia with intravenous ferric carboxymaltose in pregnancy

  • Correspondence
  • Published:
Archives of Gynecology and Obstetrics Aims and scope Submit manuscript

Abstract

Background

Iron deficiency (ID) and iron deficiency anemia (IDA) in pregnancy are global health issues, affecting around 30% of women in high-resourced countries, and increasing to over 50% of women in low-resourced countries.

Objectives

Froessler et al. study published in Archives of Gynecology and Obstetrics (2018) 298: 75. https://doi.org/10.1007/s00404-018-4782-9, raised many queries and we would like to know the answers of those queries from the authors if possible.

Results

Diagnosis of IDA should be based on hemoglobin concentration (gm/dl), serum ferritin (ug/l), mean corpuscular volume (MCV) and mean corpuscular hemoglobin (MCH), and the efficacy of the treatment of IDA evaluated by comparing pre-treatment values of hemoglobin, serum ferritin, mean corpuscular volume (MCV), and mean corpuscular hemoglobin (MCH) by the post-treatment values. Parenteral iron dose for correction of IDA calculated according to the formula; total iron needed in mg = 2.4 × pre-pregnancy weight in kg × (target hemoglobin concentration − actual hemoglobin concentration) gm/dl + 500 mg.

Conclusion

The efficacy of the treatment of IDA evaluated by comparing pre-treatment values of hemoglobin, serum ferritin, MCV, and MCH by the post-treatment values. Parenteral iron dose for correction of IDA calculated according to the formula; total iron needed in mg = 2.4 + pre-pregnancy weight in kg + (target hemoglobin concentration − actual hemoglobin concentration) gm/dl + 500 mg.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  1. Froessler B, Gajic T, Dekker G, Hodyl NA (2018) Treatment of iron deficiency and iron deficiency anemia with intravenous ferric carboxymaltose in pregnancy. Arch Gynecol Obstet 298:75. https://doi.org/10.1007/s00404-018-4782-9 [Springer Link]

    Article  CAS  PubMed Central  Google Scholar 

  2. Shafi D, Purandare SV, Sathe AV (2012) Iron Deficiency anemia in pregnancy: intravenous versus oral route. J Obstet Gynaecol India 62(3):317–321. https://doi.org/10.1007/s13224-012-0222-0 [PubMed]

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  3. Abdelazim IA, Abu-Faza M, Sanchez VJ (2014) Iron therapy in treatment of iron deficiency anemia before delivery: intravenous versus oral route. J Gynecol Obstet Med 1(1):1–7. https://doi.org/10.13140/rg.2.1.4678.8644 [Sciencescript.org]

    Article  Google Scholar 

  4. Abdelazim IA, Abu-Faza ML (2016) Sarjoun bou hamdan intravenous iron saccharate infusion for treatment of iron deficiency. ARC J Gynecol Obstet 1(3):16–20. https://doi.org/10.20431/2456-0561.0103004 [Google Scholar]

    Article  Google Scholar 

  5. Abdelazim IA, Abu-Faza M, Elbiaa AA, Othman HS, Alsharif DA, Elsawah WF (2017) Heme iron polypeptide (proferrin®-ES) versus iron saccharate complex (ferrosac) for treatment of iron deficiency anemia during pregnancy. Acta Med Int. 4:56–61. Available from: http://www.actamedicainternational.com/text.asp?2017/4/1/56/209822

    Article  Google Scholar 

  6. Abdelazim IA, Abu-Faza M, Elbiaa A, Osman H, Alsharif D, Elsawah W (2017) Heme iron to correct Iron deficiency anemia with pregnancy. Clin Obstet Gynecol Reprod Med 3(3):1–3. https://doi.org/10.15761/COGRM.1000186 [Google Scholar]

    Article  Google Scholar 

  7. Barut A, Harma M (2009) Intravenous iron treatment for iron deficiency anemia in pregnancy. J Turkish German Gynecol Assoc 10:109–115 [Scopemed.org]

    Google Scholar 

  8. Kalaivani K (2009) Prevalence and consequences of anemia in pregnancy. Indian J Med Res 130(5):627–633 [PubMed]

    CAS  PubMed  Google Scholar 

  9. Nissenson AR, Berns JS, Sakiewicz P, Ghaddar S, Moore GM, Schleicher RB et al (2003) Clinical evaluation of heme iron polypeptide: sustaining a response to rHuEPO in hemodialysis patients. Am J Kidney Dis 42(2):325–330. https://doi.org/10.1016/S0272-6386(03)00658-9 [PubMed]

    Article  CAS  PubMed  Google Scholar 

Download references

Funding

The authors have no financial disclosure to declare.

Author information

Authors and Affiliations

  1. Department of Obstetrics and Gynecology, Ahmadi Hospital, Kuwait Oil Company (KOC), P.O. Box: 9758, 61008, Al Ahmadi, Kuwait

    Ibrahim A. Abdelazim

  2. Department of Obstetrics and Gynecology, Ain Shams University, Cairo, Egypt

    Ibrahim A. Abdelazim

  3. Department of Obstetrics and Gynecology, King Hussein Medical Center (KHMC), Amman, Jordan

    Bassam Nusair

  4. Department of Obstetrics and Gynecology, Marat Ospanov, West Kazakhstan State Medical University (WKSMU), Aktobe, Kazakhstan

    Shikanova Svetlana

  5. Department of Normal and Topographical Anatomy, Marat Ospanov, West Kazakhstan State Medical University (WKSMU), Aktobe, Kazakhstan

    Gulmira Zhurabekova

Authors
  1. Ibrahim A. Abdelazim
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Bassam Nusair
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Shikanova Svetlana
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Gulmira Zhurabekova
    View author publications

    You can also search for this author in PubMed Google Scholar

Contributions

IAA is responsible for study design, Microsoft editing, and submission for publication. BN is responsible for the idea, Microsoft editing, and update of references. SS is responsible for intellectual content, update of references, and final revision before publication. GZ is responsible for Microsoft processing and final revision before publication.

Corresponding author

Correspondence to Ibrahim A. Abdelazim.

Ethics declarations

Conflict of interest

The authors have no conflict of interest to declare.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Abdelazim, I.A., Nusair, B., Svetlana, S. et al. Treatment of iron deficiency and iron deficiency anemia with intravenous ferric carboxymaltose in pregnancy. Arch Gynecol Obstet 298, 1231–1232 (2018). https://doi.org/10.1007/s00404-018-4943-x

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00404-018-4943-x

Keywords

Search

Navigation