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Biocompatible porcine dermis graft to treat severe cystocele: impact on quality of life and sexuality

  • General Gynecology
  • Published:
Archives of Gynecology and Obstetrics Aims and scope Submit manuscript

Abstract

Purpose

To study the quality of life (QoL) and sexual function changes of women affected by severe cystocele treated using biocompatible porcine dermis graft.

Methods

20 women (ranging in age from 47 to 71 years, mean age 58.7) with third- and fourth-degree cystocele (according to Baden and Walker classification) were enrolled. The Short Form-36 questionnaire to assess QoL was administrated at baseline and 12 months after surgical treatment. The Pelvic Organ Prolapse/Urinary Incontinence Sexual Questionnaire (PISQ-12) to measure the changes of sexual behavior was used at baseline and 12 months after surgical treatment. Each woman underwent translabial color Doppler ultrasonography to measure the clitoral blood flow before and 12 months after surgical treatment.

Results

Women reported QoL improvement (P < 0.001). By PISQ-12, improvement of the behavioral emotive factor score, the physical factor score, the partner-related factor score and of the total score during the 12-month follow-up with respect to baseline experience was observed (P < 0.001). Color Doppler measurement showed that the mean pulsatility index, peak systolic velocity, resistance index and end-diastolic velocity of clitoral arteries did not significantly change (P = NS).

Conclusions

Biocompatible porcine dermis graft to treat severe cystocele considerably improves QoL and sexual function, and does not influence clitoral blood flow. Our data could add new information about sexual behavior after prolapse treatment using this kind of graft, particularly about the impact on clitoral blood flow changes.

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Acknowledgments

Authors wish to express their appreciation to the women who participated in our study. The authors thank also Dr. Nazario Cassaro for critical reading of this article.

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Authors and Affiliations

  1. Department of Medical Surgical Specialties, Gynecology and Obstetrics Section, University of Catania, Via Santa Sofia 78, 95123, Catania, Italy

    Salvatore Giovanni Vitale, Salvatore Caruso, Agnese Maria Chiara Rapisarda, Gaetano Valenti, Stefano Cianci & Antonio Cianci

  2. Department of Obstetrics and Gynecology, “Papa Giovanni XXIII” Hospital, Bergamo, Italy

    Diego Rossetti

Authors
  1. Salvatore Giovanni Vitale
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  2. Salvatore Caruso
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  3. Agnese Maria Chiara Rapisarda
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  4. Gaetano Valenti
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  5. Diego Rossetti
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  6. Stefano Cianci
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  7. Antonio Cianci
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Correspondence to Salvatore Giovanni Vitale.

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Vitale, S.G., Caruso, S., Rapisarda, A.M.C. et al. Biocompatible porcine dermis graft to treat severe cystocele: impact on quality of life and sexuality. Arch Gynecol Obstet 293, 125–131 (2016). https://doi.org/10.1007/s00404-015-3820-0

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  • DOI: https://doi.org/10.1007/s00404-015-3820-0

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